Sixty consecutive surviving patients treated with subdermal BCG (5 X 10(6) organisms) have been followed up for five years after resection of lung carcinoma. A control group of the previous 60 consecutive surviving patients not treated with BCG was similarly studied. We found no statistical evidence that the administration of BCG by the method described influenced the five-year survival rate, n...

ERP – Enterprise Resources Planning is a concept broadly diffused to people and organizations since when it was coined by Gartner Group in early 1990 as the next-generation of MRP II (Keller). Very soon it became the symbol of a revolutionary change in the mode of operating company processes. Later, it was considered the solution for those organizations pressured by the year 2000 bug. Thousands...

We present a method for finding solutions of large-scale binary programming problems where the calculation of derivatives is very expensive. We then apply this method to a topology optimization problem of minimisation of weight subject to compliance and buckling constraints. We derive an analytic expression for the derivative of the stress stiffness matrix with respect to the density of an elem...

In this article, we address these shortcomings by detailing the gains achieved in the U.S. Combined Forces Command (CFC). Our experience suggests additional benefits can be gained from Y2K costs—which exceeded $3 trillion worldwide [2]—by using the experiences of Y2K testing to develop a method to improve an organization’s information technology systems. Our experience is applicable outside of ...

Introduced below is a quantum database method, not only for retrieval but also for creation. It uses a particular structure of true’s and false’s in a state vector of n qubits, permitting up to 2**2**n words, vastly more than for classical bits. Several copies are produced so that later they can be destructively observed and a word determined with high probability. Grover’s algorithm is propose...

Context. The future space missions Euclid and WFIRST-AFTA will use the Hα emission line to measure the redshifts of tens of millions of galaxies. The Hα luminosity function at z > 0.7 is one of the major sources of uncertainty in forecasting cosmological constraints from these missions. Aims. We construct unified empirical models of the Hα luminosity function spanning the range of redshifts and...

In this paper I show that an equilibrium exists to the sequential voting game in which a bandwagon begins with probability one. These bandwagons are driven by a combination of beliefs and the desire of voters to vote for the winning candidate. Signi...cantly, in this equilibrium the pivot probability for each voter is nonzero, even in an in...nite population. Consequently the bandwagons do not ...

In this paper, the design of an interval observer with an adaptive dynamical gain is presented. The observer is formulated in the framework of robust state estimation of uncertain dynamical systems, where an interval that encloses the unknown state variables is provided. For a specific type of interval observer design, an optimal gain could provide the narrowest interval. Since this gain depend...

Objective: The purpose of this study was to determine the clinical and laboratory features associated with osteonecrosis of multiple (>/= 3) joints in systemic lupus erythematosus (SLE). Methods: We included all patients with SLE and osteonecrosis evaluated at our institution between January 1, 2000 and June 30, 2006. The patients were divided into three groups based on osteonecrosis of 1 joint...

Large linear discrete ill-posed problems with contaminated data are often solved with the aid of Tikhonov regularization. Commonly used regularization matrices are finite difference approximations of a suitable derivative and are rectangular. This paper discusses the design of square regularization matrices that can be used in iterative methods based on the Arnoldi process for large-scale Tikho...