Since our first identification of plasmid-mediated colistin resistance gene mcr-1 in 2015 (Liu et al., 2016), it has been described in human clinics, domestic animals, foods, and the environment worldwide (Schwarz & Johnson, 2016). Although it is still rare, the emergence of mcr-1 in wild animals is of great concern. We summarized two previous reports on mcr-1 in wild birds from Lithuania and A...

Antibiotic resistance being called as the ‘ticking time bomb’ of the 21 st century, as the antibiotic channel is losing sheen and is on a standstill due to lack of initiatives for new antibiotic development, and other novel solutions are required for its revival. Penicillin, the oldest among the antibiotics, obtained from the Penicillium mold, was one of the first antibiotics used to treat infe...

Background: Conducting surveillance of multidrug-resistant organisms leads to identifying changes in the pathogens causing healthcare-associated infections (HAIs) of specific sites, and the antimicrobial susceptibility patterns. This surveillance study aimed to characterize the pattern of nosocomial multidrug-resistant pathogens. Methods: Clinical laboratory reports from Chiang Mai University h...

0022-2836/$ see front matter © 2009 E β-Lactamase inhibitory protein (BLIP) binds and inhibits a diverse collection of class A β-lactamases with a wide range of affinities. Alaninescanning mutagenesis was previously performed to identify the amino acid sequence requirements of BLIP for binding the TEM-1, SME-1, SHV-1, and Bla1 β-lactamases. Twenty-three BLIP residues that contact TEM-1 βlactama...

The SNAP was modified to SNAP ST (Idexx Laboratories Inc., Westbrook, ME), a new 7-8 minute test which no longer requires the use of an incubator. This new test was validated at ILVO-T&V according to Commission Decision 2002/657/EC and the CRL Guidelines for the Validation of Screening Methods (Anon., 2010). The SNAP ST is very specific as an interference was only caused by clavulanic acid, a β...

My publication (Soback et al., 1990) was criticized in a recent Letter to the Editor (Pyörälä, 2005). Pyörälä claimed that the paper should not be referenced in the report of Sérieys et al. (2005) or, for that matter, anywhere. However, Pyörälä fails to describe the alleged errors in the Soback et al. (1990) paper. I find the Soback et al. (1990) paper, for which I am the principal and correspo...

Introduction and objective: Proteus bacilli are opportunistic members of Enterobacteriaceae and Proteus mirabilis is among the most common causes of community or hospital acquired urinary tract infections (UTI) in many countries. In the present study hemolysin production, salt tolerance and resistance to antibacterial agents in environmental and UTIs samples were compared. Materials and methods...

NDM-positive Salmonella sp. strain identified in the United States. Antimicrob Agents Chemother. 2011;55:5957–8. http://dx.doi.org/10.1128/AAC.05719-11 5. Centers for Disease Control and Prevention. Carbapenem-resistant Enterobacteriaceae containing New Delhi metallo-βlactamase in two patientsRhode Island, March 2012. MMWR Morb Mortal Wkly Rep. 2012;61:446–8. 6. Centers for Disease Control and...

In recent years, infections caused by multi-drug resistant (MDR) pathogens have become a serious problem, especially in the nosocomial setting. Th e World Health Organization (WHO) has identifi ed antimicrobial resistance as one of the three most important problems for human health. Some authors have summarized this pheno menon with the word ‘ESKAPE’, to include the most frequent MDR microorgan...

Adler, M. 2014. Mechanisms and Dynamics of Carbapenem Resistance in Escherichia coli. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 998. 51 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-554-8950-2. The emergence of extended spectrum β-lactamase (ESBL) producing Enterobacteriaceae worldwide has led to an increased use of carbapenems and may driv...