The induction and synthesis of metallothionein was studied in the isolated perfused rat liver, using Cd(I1) as the inducing metal. Perfusing the liver with 25 to 100 pg of Cd(I1) for 180 min revealed that the amount of Cd(I1) in metallothionein increased with the dosage of Cd(II), saturation being achieved at 75 pg. Zn(I1) in metallothionein decreased to about 60% of the level found in control ...

Alternative splicing (AS) is one of the most significant components of the functional complexity of human UDP-glucuronosyltransferase enzymes (UGTs), particularly for the UGT1A gene, which represents one of the best examples of a drug-metabolizing gene regulated by AS. Shorter UGT1A isoforms [isoform 2 (i2)] are deficient in glucuronic acid transferase activity but function as negative regulato...

This paper extends the analysis of the relationship between health and schooling by examining the impact of education on the choice of medical care inputs and the subsequent relationship between these inputs and overall health. In particular, we examine the productive effects of education on health as well as the allocative effects of education on the consumption of curative and preventive medi...

Let I1 be a relation structure. We say that I1 is discrete if and only if: (Def. 1) The internal relation of I1 = △the carrier of I1. Let us mention that there exists a poset which is strict discrete and non empty and there exists a poset which is strict discrete and empty. Let X be a set. Then △X is an order in X. Observe that 〈∅,△∅〉 is empty. Let P be an empty relation structure. One can chec...

The necessity of the inclusion second invariant left Cauchy-Green deformation tensor B, namely I2, in strain energy function W rubber-like materials is analysed. Universal relationships that underline such are revisited, and experimental data examined to establish trends variation ?W/?I2. Corroborated by established trends, we consider (meso)structural arguments devise a plausible approach for ...