Tamoxifen (TAM), used as the endocrine therapy of choice for breast cancer, undergoes metabolism primarily forming N-desmethyltamoxifen, 4-hydroxytamoxifen, alpha-hydroxytamoxifen, and tamoxifen-N-oxide (TNO). Our earlier studies demonstrated that flavin-containing monooxygenases (FMOs) catalyze the formation of TNO. The current study demonstrates that human FMO1 and FMO3 catalyze TAM N-oxidati...

Unlike most conventional anode materials, the newly developed TiNb2O7 (TNO) does not form a solid electrolyte interface (SEI) layer, which makes it safe for high power requiring lithium-ion batteries. In this paper, we demonstrated an SBA-15 confined synthetic approach to prepare TNO nanoparticles (S-TNO) with a small particle size around 10 nm and a large BET surface area of 79.5 m(2) g(-1). I...

PURPOSE It has been repeatedly shown that the TNO stereotest overestimates stereo threshold compared to other clinical stereotests. In the current study, we test whether this overestimation can be attributed to a distinction between 'global' (or 'cyclopean') and 'local' (feature or contour-based) stereopsis. METHODS We compared stereo thresholds of a global (TNO) and a local clinical stereote...

In this study, indium–tin oxide (ITO)/Nb-doping TiO2 (TNO) double-layer transparent conductive (TCO) films deposited using DC magnetron sputtering were used as a surface anti-reflection layer with an overall thickness of 100 nm for films. The simulated results showed that ITO and TNO combinations 90 nm/10 nm, 80 nm/20 70 nm/30 had higher transmittance lower reflectance than others in the visibl...

Purpose: To develop stereoacuity test using a high-resolution 3D monitor and examined the effects of the monitor on the measured stereoacuity. Methods: We conducted stereoacuity test using a high-resolution 3D monitor. This 3D monitor can show parallax of 27 s (crossed) at the minimum at measurement distance 40 cm, and circularly polarized glasses were used for binocular separation. Titmus ster...

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