i ntroduction: apical debris extrusion (de) subsequent to root canal instrumentation, is one of the most important causes of endodontic flare-ups. the aim of this study was to compare the amount of de after root canal instrumentation using nickel-titanium (niti) hand files with step-back manual technique or installed on reciprocating handpiece. methods and materials: this study was conducted on...

a Harvard T.H. Chan School of Public Health, Department of Epidemiology, Program on Integrative Knowledge and Human Flourishing, Harvard University, National Consortium on Psychosocial Stress, Spirituality, and Health, United States b Harvard Medical School, Harvard/MGH Center on Genomics, Vulnerable Populations, and Health Disparities, National Consortium on Psychosocial Stress, Spirituality, ...

Understanding the causes of diabetes is at the heart of most diabetes research. The field of causal inference has made dramatic advances in methodology that allows for causal inference from observational and not experimental data (1). One such methodological advancement is the use of genetic markers as instrumental variables, or so-called Mendelian randomization (MR) (2). MR relies on the laws ...

the incremental sheet metal forming (ismf) process is a new and flexible method that is well suited for small batch production or prototyping. this paper studies the use of the finite element method in the incremental forming process of aa1050 sheets to investigate the influence of tool diameter, vertical step size, and friction coefficient on forming force, spring-back, and thickness distribut...