The growth-inhibitory effect of cyclocreatine (CCr) and the kinetics of CCr and Na+ cotransport were investigated in MCF7 human breast cancer cells and its adriamycin-resistant subline with use of 31P- and23Na-NMR spectroscopy. The growth-inhibitory effect in the resistant line occurred at a lower CCr concentration and was more pronounced than in the wild-type line. This correlated with an ∼10-...

Aim of this study was to evaluate, in Renal Transplant Recipients (RTR), a new method to predict Creatinine Clearance (Ccr) from Plasma Creatinine (Pcr) and from the value of Body Cell Mass (BCM). The values of BCM were obtained, from body impedance analysis (BIA) using an impedance plethysmograph, in 87 RTR with different graft function. The ratios of 24-hour Urinary Creatinine Excretion (Ucr)...

Data Envelopment Analysis (DEA) is the use of non-parametric mathematical programming that useful for measuring efficiency Decision Making Unit (DMU) an organization. This study uses Cooper and Rhodes (CCR) method known as DEA-CCR multiplier which aims to determine weight value each input output variable DMU being evaluated, but it not sufficient measure optimization. To get efficient a referen...

OBJECTIVE Although it is accepted that elevated plasma homocysteine (tHcy) levels occur in end-stage renal disease and type 2 diabetes, the changes with milder renal dysfunction (e.g., microalbuminuria) are less clearly established. This study explores the relationship among tHcy, creatinine clearance (Ccr), and albumin excretion rate (AER) in a population with type 2 diabetes. RESEARCH DESIG...

OBJECTIVES Extension of the standard model while retaining compliance with it is a challenging issue because there is currently no method for semantically or syntactically verifying an extended data model. A metadata-based extended model, named CCR+, was designed and implemented to achieve interoperability between standard and extended models. METHODS Furthermore, a multilayered validation me...

PURPOSE To determine the suppressive effects of antibodies (Abs) against CC-chemokine receptor (CCR)-1 and CCR-3 on eosinophil chemotaxis induced by culture supernatant from corneal keratocytes and by tears from severely allergic patients with corneal ulcer. METHODS Primary cultures of human corneal keratocytes were incubated with interleukin (IL)-4 (33.3 ng/mL) and tumor necrosis factor (TNF...