Male Drosophila are monosomic for the X chromosome, but survive due to dosage compensation. They use the Male Specific Lethal (MSL) complex composed of noncoding roX RNA and histone modifying enzymes to hypertranscribe most genes along the X ∼1.6-1.8 fold relative to each female allele. It is not known how the MSL complex achieves this precise adjustment to a large and diverse set of target gen...

Three-dimensional tissue cultures have been used as effective models for studying different diseases, including epilepsy. High-throughput, nondestructive techniques are essential for rapid assessment of disease-related processes, such as progressive cell death. An ultrahigh-resolution optical coherence microscopy (UHR-OCM) system with [Formula: see text] axial resolution and [Formula: see text]...

PURPOSE Prostate cancer metastasizes to the skeleton to form osteoblastic lesions. Androgen ablation is the current treatment for metastatic prostate cancer. This therapy is palliative, and the disease will return in an androgen-independent form that is preceded by a rising titer of prostate-specific antigen (PSA). Here, we investigated the possibility that human osteoblasts might secrete facto...

Gabor-domain optical coherence microscopy (GD-OCM) is a volumetric high-resolution technique capable of acquiring three-dimensional (3-D) skin images with histological resolution. Real-time image processing is needed to enable GD-OCM imaging in a clinical setting. We present a parallelized and scalable multi-graphics processing unit (GPU) computing framework for real-time GD-OCM image processin...

We report the enhancement in imaging performance of a spectral-domain optical coherence microscope (OCM) in turbid media by incorporating an optical parametric amplifier (OPA). The OPA provides a high level of optical gain to the sample arm, thereby improving the signal-to-noise ratio of the OCM by a factor of up to 15 dB. A unique nonlinear confocal gate is automatically formed in the OPA, whi...

Oxidative coupling of methane (OCM) is an exothermic reaction that results in the temperature rise towards latter part reactor. This study reports consequence OCM product distribution after O 2 depletion at high temperatures.

We report an imaging study using integrated 3D-OCT and OCM for the assessment of various human thyroid and breast pathologies. The 3D-OCT data sets enable en face projection imaging, which provides large field of view with uniform focus and signal level, while OCM provides high magnification that enables cellular resolution imaging. We have demonstrated that the integrated 3D-OCT and OCM techno...

for more than three decades, oxidative coupling of methane (ocm) process has been comprehensively investigated as an attractive alternative for the commercially available ethylene production technologies such as ethane and naphtha cracking. developing a suitable catalyst and proper reactor feeding policy, reviewing and deploying the efficient methods in the separation and purification of the un...

oxidative coupling of methane has been studied over (mn+a+w)/sio2 catalysts in a continuous–flow microreactor, where a represents an alkali ion of li, na, k or cs having different weight percents. the main aim of this study is to find the role of alkali ions in interaction between mn and w species with sio2 to make a proper structure for catalyzing oxidative coupling of methane (ocm) reaction. ...

One-carbon metabolism (OCM) is linked to DNA synthesis and methylation, amino acid metabolism and cell proliferation. OCM dysfunction has been associated with increased risk for various diseases, including cancer and neural tube defects. MicroRNAs (miRNAs) are ∼ 22 nt RNA regulators that have been implicated in a wide array of basic cellular processes, such as differentiation and metabolism. Ac...