MDL 62,879 (GE2270 A) is a new peptide antibiotic that inhibits protein synthesis through an interaction with elongation factor Tu. MDL 62,879 was very active against gram-positive clinical isolates, particularly staphylococci and enterococci, for which MICs for 90% of isolates were < or = 0.13 micrograms/ml. It was equally active against isolates resistant to beta-lactams, erythromycin, gentam...

The title compound, C(56)H(56)Ge(4)O(2)·2CH(2)Cl(2) or Tol(8)Ge(4)O(2)·2CH(2)Cl(2) (Tol = p-CH(3)C(6)H(4)), was obtained serendipitously during the attempted synthesis of a branched oligogermane from Tol(3)GeNMe(2) and PhGeH(3). The mol-ecule contains an inversion center in the middle of the Ge(4)O(2) ring which is in a chair conformation. The Ge-Ge bond distance is 2.4418 (5) Å and the Ge-O bo...

The neutral germanium(i) dimers, [{Ge(Piso)}(2)] and [{Ge(Giso)}(2)], Piso = [(ArN)(2)CBu(t)](-), Giso = [(ArN)(2)CNPr(i)(2)](-), Ar = C(6)H(3)Pr(i)(2)-2,6, which are stabilised by bulky amidinate and guanidinate ligands respectively, have been prepared by reduction of the corresponding germanium(ii) chlorides, [Ge(Piso)Cl] and [Ge(Giso)Cl]; theoretical studies suggest that the Ge-Ge bonds of [...

Bovine herpesvirus type 5 (BoHV-5) is an important pathogen of cattle in South America. We describe here the construction and characterization of deletion mutants defective in the glycoprotein E (gE) or thymidine kinase (TK) gene or both (gE/TK) from a highly neurovirulent and well-characterized Brazilian BoHV-5 strain (SV507/99). A gE-deleted recombinant virus (BoHV-5 gE) was first generated i...

Abstract In this paper, the notions of maximal GE-filter and prime a GE-algebra are introduced relation between them is given. Some characterizations GE-filters transitive given in terms generated by subset GE-algebra. We generalized Stone’s theorem to GE-algebras. The notion elitable bordered investigated its properties. observed that class all complete distributive lattice. Equivalent conditi...

Density functional theory was used to performed a survey of transition metal oxide (MO2 = ZrO2, HfO2) ordered molecular adsorbate bonding configurations on the Ge(100)-4 2 surface. Surface binding geometries of metal-down (O–M–Ge) and oxygen-down (M– O–Ge) were considered, including both adsorbate and displacement geometries of M–O–Ge. Calculated enthalpies of adsorption show that bonding geome...

Grammatical Evolution (GE), which is one of the evolutionary computations, aims to find function, program or program segment satisfying the design objective. This paper describes the improvement of the Grammatical Evolution according to Stochastic Schemata Exploiter (GE-SSE) and its application to symbolic regression problem. Firstly, GE-SSE is compared with original GE in symbolic regression p...

Metabolic syndrome (MetS) is a major metabolic disorder worldwide which is characterized by having three or more of the five metabolic abnormalities. These metabolic abnormalities include abdominal obesity (waist circumference &ge; 90 cm for men and &ge; 80 cm for women), high triglyceride levels (TG) (&le; 150 mg/dL), decreased high density lipoprotein cholesterol (HDL-c) (< 40 mg/dL in men an...