The present study was initiated because of concerns expressed by NHLBI-funded mid-career investigators regarding perceived difficulties in the renewal of their grant awards. This led us to ask: "Are mid-career investigators experiencing disproportionate difficulties in the advancement of their professional careers?" Our portfolio analysis indicates that there has been a significant and evolving...

Nateglinide(NTG), Repaglinide(RPG), and Glimepiride(GMP) are antidiabetic drugs. These antidiabetic drugs are poorly soluble in water, which affect the bioavailability. In the present work, complex formation of all the three drugs with b-cyclodextrin (b-CD) and Hydroxy propyl bcyclodextrin (HPb-CD) and then the possibility of improving the solubility of NTG, RPG and GMP by complexation with b-C...

OBJECTIVE To determine whether random plasma glucose (RPG) collected from patients without known impaired glucose metabolism (IGM) in the emergency department (ED) is a useful screen for diabetes or prediabetes. DESIGN Retrospective cohort study. SETTING ED of a Canadian teaching hospital over 1 month. PARTICIPANTS Adult patients in ED with RPG over 7 mmol/L were recruited for participati...

Este artigo tem o objetivo de refletir por meio analogias sobre competências e características éticas dentro da categoria jogo role-playing game (RPG), adotando uma perspectiva educativa crítico-filosófica. Com base em pesquisa bibliográfica, presente estudo enfatiza como um dado jogador quase nada conseguirá agindo maneira egoísta, já que a cooperação as escolhas prol do bem maioria são fator ...

PURPOSE We evaluated the relationship between dosimetric parameters (DPs) and the incidence of radiation pneumonitis (RP) and investigated the feasibility of a proposed treatment planning technique with the potential of reducing RP in esophageal cancer patients treated with definitive chemoradiotherapy using extended fields. PATIENTS AND METHODS A total of 149 patients with locally advanced e...

In 21 Century, through the E-learning, students can be fostered the abilities of critical thinking and skills of problem solving. Resulting from this learning, learners can apply their learned knowledge in daily problem solving and can create a new attitude to their living. This study is to develop a new computer Role-Playing Game (RPG). In the game, it will blend the ideas of RPG and theory of...

Nowadays Games become an entertainment alternative for various circles, industry and game development business is also a profitable industry. In Indonesia the amount of game consumption is very high, especially the console game type RPG (Role Playing Game). The task of this research is developing game software using Unity3d to create an Android-based RPG game app. The story is packed with RPG g...

RPG is a game genre that focuses the cooperative interaction among players, as well as socialization and the improvement of communication skills. As these actions form the very context of these games, RPGs have an inherent level of decision-making that naturally occurs at all times throughout the course of the game. Those reasons led the idea to take advantage of the RPG genre to design a model...

Heterozygous inactivating mutations in ribosomal protein genes (RPGs) are associated with hematopoietic and developmental abnormalities, activation of p53, and altered risk of cancer in humans and model organisms. Here we performed a large-scale analysis of cancer genome data to examine the frequency and selective pressure of RPG lesions across human cancers. We found that hemizygous RPG deleti...