Buruli Ulcer is a neglected tropical disease leading to extensive disabilities and morbidity in West Africa. In this paper we sought to characterize various strains of Mycobacterium ulcerans (M.ulcerans) with different origins and laboratory passage records while refining a mouse model for Buruli ulcer. We described, compared and followed the kinetics of the histo-pathological outcome of infect...

محاسبه دز جذبی در اندام انسان یکی از اولین گام‌­ها برای توسعه رادیوداروهای جدید است. هدف این مطالعه تخمین توسط ترکیب نوین نشاندار Cu-NODAGA-RGD-BBN64 بدین‌منظور ابتدا با تغییر پارامترهای مؤثر بر نشاندارسازی شرایط بهینه تهیه شد. پایداری پپتید هترودیمر بافر سالین فسفات (PBS) و سرم خون انسانی به مدت 12 ساعت ارزیابی پس آن، توزیع زیستی کمپلکس موش‌های حامل تومور تزریق مورد بررسی قرار گرفت. نهایت، اسا...

Susceptibility to Theiler's murine encephalomyelitis virus-induced demyelination (TMEVD), a mouse model for multiple sclerosis (MS), is genetically controlled. Through a mouse-human comparative mapping approach, identification of candidate susceptibility loci for MS based on the location of TMEVD susceptibility loci may be possible. Composite interval mapping (CIM) identified quantitative trait...

Graves' disease (GD) is an autoimmune condition in which goitre and hyperthyroidism are induced by thyroid stimulating antibodies (TSAB) which mimic the action of thyrotrophin (TSH). The target of the autoimmune response is the thyrotrophin receptor (TSHR) and, since its cloning, a number of differing approaches have been adopted in an attempt to develop an animal model of GD. Methods in which ...

In this study, it was aimed to investigate the effects of different diets on lipid peroxidation, antioxidants, proliferation and vasculogenesis in liver tissue. BALBC female rats (21) were divided as group fed with standard chow (SC), a ketogenic diet (KD) western (WD). The tap water rat specially prepared according determined for 4 weeks. Liver tissue oxidative damage, evaluated using spectrop...

Senyawa tanin yang terdapat di teh dapat membentuk kompleks mengakibatkan terjadinya obstruksi ureter, pembengkakan ginjal (Hidronefrosis). Prevelansi gagal Indonesia disebabkan hidronefrosis dari tahun ke terus meningkat pada 2011 jumlah penderita adalah 22.304 dan 2012 menjadi 28,782 kasus. Penelitian ini bertujuan untuk mengetahui prevalensi kejadian Musmuculus Bablc Albino diberikan ekstra ...