The immunogenicity and efficacy of three inactivated vaccines (A, B, C) prepared with Mycoplasma agalactiae (M. agalactiae) and with different oil-emulsion adjuvants were evaluated in sheep. Twenty-eight animals were used, divided into four groups (a, b, c, d) of seven animals each. Three groups were immunized with the same vaccine, but using different adjuvants, while one group (d) was used as...

Cocktail-party Problems (increasing generality): • Independent component analysis (ICA) [1, 2]: onedimensional sound sources. • Independent subspace analysis (ISA) [3]: independent groups of people. • Blind source deconvolution (BSD) [4]: one-dimensional sound sources and echoic room. • Blind subspace deconvolution (BSSD) [5]: independent source groups and echoes. Separation Theorem: • ISA ([3]...

Chickens were immunized subcutaneously with an Eimeria recombinant profilin protein plus Montanide™ ISA 70 VG (ISA 70) or Montanide™ ISA 71 VG (ISA 71) water-in-oil adjuvants, or with profilin alone, and comparative RNA microarray hybridizations were performed to ascertain global transcriptome changes induced by profilin/ISA 70 vs. profilin alone and by profilin/ISA 71 vs. profilin alone. While...

The poly(amidoamine)s (PAAs) ISA 1 and ISA 23 display pH-dependent conformational change and pH-dependent membrane perturbation. These properties confer potential for use as endosomolytic polymers for intracytoplasmic delivery of toxins and genes. Both polymers are relatively non-toxic, and moreover ISA 23 has the beneficial property in vivo, of being non hepatotropic when administered intraven...

Currently organizations, pushed by several business and technological changes, are more concern about Information systems (IS) than ever. Though organizations usually still face each IS as a separately technological issue with slight relations with business domain. This paper discusses the importance of the Information System Architecture (ISA) as the tool for ensuring a global view on IS and f...

Impervious surface area (ISA) is considered as an indicator of environment change and is regarded as an important input parameter for hydrological cycle simulation, water management and area pollution assessment. The Pearl River Delta (PRD), the 3rd most important economic district of China, is chosen in this paper to extract the ISA information based on Landsat images of 1998, 2003 and 2008 by...

Background. Isavuconazole (ISA) is a once-daily, extended-spectrum triazole approved for treatment of invasive aspergillosis and mucormycosis. The pharmacokinetic profile, daily dosing, lack of therapeutic drug monitoring (TDM) and reduced cost make ISA a promising option for use as prophylaxis for invasive fungal infections (IFIs). We report our experience with use of ISA for prophylaxis of IF...

This study is a part of an ongoing ISA project in Denmark. Its aim was to clarify two human factors issues, (1) the difference in attitude between ISA-volunteers and non-volunteers, and (2) the relative impact on speeding of two factors, ISA-information and driver motivation. The first part of the study compared survey data from ISA-volunteers with those of non-volunteers. The two groups differ...

Background. Isavuconazole (ISA) is a once-daily, extended-spectrum triazole approved for treatment of invasive aspergillosis and mucormycosis. The pharmacokinetic profile, daily dosing, lack of therapeutic drug monitoring (TDM) and reduced cost make ISA a promising option for use as prophylaxis for invasive fungal infections (IFIs). We report our experience with use of ISA for prophylaxis of IF...