BACKGROUND CTX-M-55 extended-spectrum beta-lactamases are being rapidly disseminated and transmitted in clinical practices around the world. The genetic contexts of the transferable plasmid-mediated blaCTX-M-55 gene in Enterobacteriaceae were detected and characterized in this study. METHODS Isolates were obtained from the First Affiliated Hospital of Zhengzhou University between September 20...

Members of the globally important CTX-M group of extended-spectrum -lactamases fall into at least six subgroups (CTX-M-1, -2, -8, -9, -25, and KLUC [ 90% amino acid identity between subgroups]), with members of each subgroup differing by one or a few amino acid changes (1). Ancestral members of the different blaCTX-M subgroups appear to have been captured from the chromosomes of different Kluyv...

Background The CTX-M family of extended-spectrum beta lactamase (ESBL) enzymes is comprised of over 60 blaCTX-M gene variants with the predominance of blaCTX-M-15 in many regions. In this report, we present the first description of blaCTX-M-28 in the United Arab Emirates. Methods Forty-five non-duplicate ESBL producing isolates identified in a secondary care facility in the United Arab Emirat...

In view of continued high clinical prevalence of infections involving extended-spectrum β-lactamase (ESBL)-producing Escherichia coli, this study sought to characterise the blaCTX-M genes, their associated mobile genetic elements and the integrons present in 100 ESBL-producing E. coli isolates collected in a Dublin hospital and associated community healthcare facilities. Polymerase chain reacti...

Pseudomonas aeruginosa is one of the most common opportunistic pathogens that cause infections. The drug resistance in may relate to production broad spectrum beta lactamase enzymes. This study aimed detect multidrug resistant, extensively resistant and pan isolates determine frequency extended lactamases enzymes by using a reliable test for detection blaCTX-M1, blaCTX-M2 blaCTX-M3 genes aerugi...

The dissemination of plasmid-mediated antimicrobial resistance genes may pose a substantial public health risk. In the present work, the occurrences of blaCTX-M and plasmid-mediated ampC and qnr genes were investigated in Escherichia coli from 16 chicken carcasses produced by four commercial brands in Brazil. Of the brands tested, three were exporters, including one of organic chicken. Our stud...