Endothelial dysfunction, with impaired bioavailability and/or bioactivity of the vasoprotective molecule, nitric oxide, appears to be a vital step in initiation atherosclerosis. Several studies have shown that dietary nitrate/nitrite can significant benefits on human cardiovascular homeostasis. Although serum nitrite concentrations reach micromolar levels, physiological significance normal tiss...

endothelial nitric oxide synthase (enos) produces nitric oxide (no) from l-arginine and is important for the maintenance of cardiovascular homeostasis. congestive heart failure (chf) generally results in increased pulmonary blood flow and if untreated leads to pulmonary hypertension and end stage heart failure. we therefore hypothesized that increased pulmonary flow without changes in pressure ...

Background: This is a case-control study to determine the relationship between endothelial nitric oxide synthase (eNOS) gene -786T/C polymorphism in women with unexplaiend recurrent abortion in comparison with healty women.Materials and Methods: 95 women with history of at least 2 unexplaiend recurrent abortion in the reproductive age range 20-35 years as patients group and 95 healty women (age...

Abstract Objectives Aside from the activity of gaseous transmitter molecule nitric oxide (NO) and cyclic GMP producing enzyme soluble guanylyl cyclase (sGC) in human penile erectile tissue, intracellular receptor proteins activated by binding have been considered to play a significant role erection process. In animal models, down-regulation GMP-dependent/binding protein kinase I (cGKI) has link...

Endothelial nitric oxide synthase (eNOS) plays a critical role in regulating and maintaining healthy cardiovascular system. The importance of eNOS can be emphasized from the genetic polymorphisms gene, uncoupling dimerization, its numerous signaling regulations. activity on cardiac myocytes, vasculature, central nervous system are discussed. effects sympathetic autonomic (SANS) parasympathetic ...

Background: Nitric oxide (NO) produced by endothelial NO synthase (eNOS) mediates a large range of processes, and abnormality in the production of NO has been implicated in diabetic complications including diabetic nephropathy (DN). G894T polymorphism in the eNOS gene has been shown to decreased activity the NO levels of plasma. The association between eNOS Glu298Asp gene polymorphism and DN ri...

background:   objective: the aim of this study was to evaluate the expression of enos in the fts of women with tep.   materials and methods: in this case-control study, a total number of 30fts samples were obtained from three groups including: 10 fts of women that bearing an ep, 10 fts from the non-pregnant women at luteal phase of the menstrual cycle, and 10 fts of healthy pregnant women (n=10...

background: non obstructive azoospermia (noa) is one of the causes of male infertility in which spermatogenesis process is disturbed. recent studies suggested the possible role of endothelial nitric oxide synthase (enos) in spermatogenesis process. objective: the aim of the present study is to evaluate the expression of enos in human testicular tissue in men with noa and men with normal spermat...

Consideraciones respecto al efecto del evento La Niña de ENOS.