We confirmed multiple picoeukaryotic algae, Ostreococcus, Micromonas, and Pelagomonas spp., as thiamine (vitamin B1) auxotrophs in laboratory experiments with axenic cultures. Examined strains have half saturation growth constants (Ks) for B1 between 1.26 and 6.22 pmol B1 L , which is higher than reported seawater concentrations. Minimum B1 cell quotas for Ostreococcus and Micromonas spp. are h...

TGF-b1 and VEGF, both angiogenesis inducers, have opposing effects on vascular endothelial cells. TGF-b1 induces apoptosis; VEGF induces survival. We have previously shown that TGF-b1 induces endothelial cell expression of VEGF, which mediates TGF-b1 induction of apoptosis through activation of p38mitogen-activated protein kinase (MAPK). Because VEGF activates p38 but protects the cells from ap...

Bois noir, an economically important disease of grapevine yellows that causes significant economic losses in wine production, is associated with ‘Candidatus Phytoplasma solani’ and transmitted to grapevines by cixiids Hyalesthes obsoletus Reptalus panzeri. Polyphagous planthopper Dictyophara europaea, commonly found natural habitats, harbors phytoplasmas from distinct groups alternative vector ...

5,981,180 A 11/1999 Chandleret a1. 6,046,807 A 4/2000 Chandler 6,139,800 A 10/2000 Chandler 6,268,222 B1 7/2001 Chandleret a1. 6,366,354 B1 4/2002 Chandler 6,449,562 B1 9/2002 Chandler et a1. 6,514,295 B1 2/2003 Chandleret a1. 6,524,793 B1 2/2003 Chandleret a1. 6,592,822 B1 7/2003 Chandler 6,599,331 B2 7/2003 Chandleret a1. 6,632,526 B1 10/2003 Chandler 6,649,414 B1 11/2003 Chandler et a1. 6,69...

Endophilin-B1, also known as Bax-interacting factor 1 (Bif-1, and encoded by SH3GLB1), is a multifunctional protein involved in apoptosis, autophagy and mitochondrial function. We recently described a unique neuroprotective role for neuron-specific alternatively spliced isoforms of endophilin-B1. To examine whether endophilin-B1-mediated neuroprotection could be a novel therapeutic target for A...

Perception of photoperiod changes enables plants to flower under optimum conditions for survival. We used doubled haploid populations of crosses among Avalon × Cadenza, Charger × Badger and Spark × Rialto and identified short-day flowering time response quantitative trait loci (QTL) on wheat chromosomes 1BS and 1BL. We used synteny between Brachypodium distachyon and wheat to identify potential...

A human B-cell lymphoma xenograft model was used to test whether the administration of unlabeled MoAb prior to injection of radiolabeled monoclonal antibody (MoAb) improves delivery of the radiolabeled MoAb to tumor prior to testing in clinical radioimmunotherapy trials. The anti-B1/CD20 pan-B-cell MoAb reactive with human B-cell lymphomas and leukemias but not reactive with mouse B-cells was u...

PURPOSE: The BEAR method is a recently proposed phase-based B1 mapping method. An important feature of BEAR is that the phase sensitivity to B1 can be manipulated with sequence parameters. We describe a new method that calculates the B1 distribution in a volume from multiple 1D BEAR projections, where each projection has a different B1 sensitivity. In essence, we are replacing spatial phase enc...