A heuristic procedure is developed to assign buses to transit centers (garages) in such a way that all the buses on a particular route are assigned to a single transit center. This research builds on an optimal mixed integer programming location/allocation model that splits the bus assignments when capacity limitations were reached at a transit center. The heuristic procedure adopts a two-step ...

We study thermomechanical deformations of a viscoplastic body deformed in simple shear. The e€ect of material elasticity is neglected but that of work hardening, strain-rate hardening, thermal softening, and strain-rate gradients is considered. The consideration of strain-rate gradients introduces a material characteristic length into the problem. A homogeneous solution of the governing equatio...

With respect to the long-life missions associated with NASA’s X2000 Advanced Deep-Space System Development Program, reliability implies a system’s continuous operation for many years in an unsurveyed radiation-intense environment. Further, the stringent constraints on the mass of a spacecraft and the power on-board create unprecedented challenges on the means for achieving the ultra-high missio...

1 This work was supported by the NIH-NIAID via grants R01 A105624 and U19 A1084024 to T.D. and by a grant from the Magee Women’s Research Institute Clinical Trainee Research Award to T.E.C. 2 Author is now located at the Department of Pediatrics, Penn State Hershey School of Medicine, 500 University Drive, Hershey, Pennsylvania 17033. CVI Accepts, published online ahead of print on 2 April 2014...

I discuss the measurement of the parity violating left-right asymmetry in the scattering of high energy polarized electrons from the atomic electrons in a liquid hydrogen target. The asymmetry, due to the interference between the weak and electromagnetic amplitudes, measures the product of the vector and axialvector couplings of the electron to the Z boson, and is thus proportional to 1 4 sin W...

ABSTRACT Objective: to construct the conceptual and operational definitions of defining characteristics related factors nursing diagnosis (ND) hypothermia (00006) NANDA-I, 2015-2017, in adult patients perioperative period. Method: an integrative literature review Medical Literature Analysis Retrieval System Online, Cochrane Library, The Cumulative Index Nursing Allied Health Latin & America...

Submit Manuscript | http://medcraveonline.com MOJ Anat Physiol 2015, 1(2): 00006 was neonatal lethal. Due to background modifications, a small percentage of knockout mice showed dilated cardiomyopathy indicating increased vulnerability to oxidative injury in the cardiac myocytes [1]. Ikegami et al. [3] successfully generated tissuespecific MnSOD conditional knockout mice that would provide a us...

Thirty cases of newly diagnosed pediatric acute myeloblastic leukemia (AML) with French-American-British (FAB) M2 morphology were analyzed with cytogenetics and a comprehensive panel of monoclonal antibodies reactive with lymphoid-, natural killer (NK)-cell-, and myeloid-associated antigens. The t(8;21)(q22;q22), or t(8;21;V)(q22;q22;V), translocation was identified in 16 of the 30 cases. Cases...

Kidney glomeruli are important targets of diabetic nephropathy. We hypothesized a high concentration of glucose could suppress glomerular eNOS by a protein kinase C mechanism, as has been found in other tissues. Mouse kidney slices (150-200 μm) were bathed in Hank's solution with 100 μM L-arginine and exposed to either 5 mM or 20-30 mM D-glucose. Immunofluorescence identified only eNOS in norma...

The Cloud Computing paradigm focuses on the provisioning of reliable and scalable infrastructures (Clouds) delivering execution and storage services. The paradigm, with its promise of virtually infinite resources, seems to suit well in solving resource greedy scientific computing problems. The goal of this work is to study private Clouds to execute scientific experiments coming from multiple us...