This Classic Article is a reprint of the original work by Hiroshi Nogami and Marshall R. Urist, A Morphogenetic Matrix for Differentiation of Cartilage in Tissue Culture. An accompanying biographical sketch of Marshall R. Urist, MD is available at DOI 10.1007/s11999-009-1067-4; a second Classic Article is available at DOI10.1007/s11999-009-1068-3; and a third Classic Article is available at DOI...

Introduction Periodic Fever, Aphthous stomatitis, Pharyngitis and Adenitis (PFAPA) syndrome is an autoinflammatory disorder of childhood and little is known about the underlying etiology. While mutations involving the IL-1 pathway have been identified in other recurrent fever disorders, including TNF-receptor associated periodic syndrome (TRAPS) and cryopyrin-associated periodic syndrome (CAPS)...

Introduction CANDLE syndrome is an exceptional inflammatory condition starting within the first months of life, and comprising elevated fever, panniculitis with lipoatrophy, purplish and swollen eyelids, arthralgia, and developmental retardation. Most patients carry homozygous mutations in the PSMB8 gene that impair the assembly of the immunoproteasome (iP) and lead to interferon g deregulation...

Following the success of the previous edition held in Durham in 2007, MALLOW-AWESOME’009 wants to stimulate discussion among researchers working on Agents, Web Services, and Ontologies, in order to help the identification and the definition of Methodologies for integrating them. The realisation of distributed, open, dynamic, and heterogeneous software systems is, in fact, a challenge that invol...

This study was undertaken in order to identify and describe the nature of socialization of females into sport. A fixed-alternative questionnaire was administered to 585 women who were currently active in sport. Results indicated that peers and family were the significant agents of socialization during childhood, peers and school were aost significant during adolescence, and peers were most sign...

This biographical sketch of Ignacio V. Ponseti, MD, corresponds to the historic text, The Classic: Congenital Club Foot: The Results of Treatment, available at DOI 10.1007/s11999-009-0720-2 and The Classic: Observations on Pathogenesis and Treatment of Congenital Clubfoot, available at DOI 10.1007/s11999-009-0721-1.

Citation: Hermann RM, Schober M, Carl UM, Nitsche M (2016) Three Simple Software Extensions for Automatic Presentation of Radiation Induced Toxicity, Sequelae and Treatment Outcomes, for Increasing Safety in Daily Therapeutic Routine, and for Enhancing Patient Comfort. Int J Radiol Radiat Oncol 2(1): 009-011. 009 safety, and to improve patient satisfaction in a very cost effective way in daily ...

Background: Mesothelin is a tumor differentiation antigen; its binding to tumor-antigen CA-125 can lead to tumor metastasis. Results: Structures of the Fab from a therapeutic antibody MORAb-009 and its complex with an epitope-containing fragment of mesothelin are obtained. Conclusion: Overlapping binding sites for both CA-125 and MORAb-009 provides a basis for the antibody’s therapeutic effect....