نتایج جستجو برای: 0154

تعداد نتایج: 62  

2016
Ryan Martin

Number of Papers published in peer-reviewed journals: Number of Papers published in non peer-reviewed journals: Final Report: Variations on Bayesian Prediction and Inference Report Title A Bayesian approach, based on updating prior information in light of new observations, via Bayes's formula, has both nice intuition and strong theoretical support. However, in some applications, there are some ...

Journal: :Blood 2011
Duane A Mitchell Xiuyu Cui Robert J Schmittling Luis Sanchez-Perez David J Snyder Kendra L Congdon Gary E Archer Annick Desjardins Allan H Friedman Henry S Friedman James E Herndon Roger E McLendon David A Reardon James J Vredenburgh Darell D Bigner John H Sampson

Lymphodepletion augments adoptive cell transfer during antitumor immunotherapy, producing dramatic clinical responses in patients with malignant melanoma. We report that the lymphopenia induced by the chemotherapeutic agent temozolomide (TMZ) enhances vaccine-driven immune responses and significantly reduces malignant growth in an established model of murine tumorigenesis. Unexpectedly, despite...

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