ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Maciejewska M, Czuwara J, Olszewska Rudnicka L. Quiz dermatologiczny. Dermatology Review/Przegląd Dermatologiczny. 2022;109(6):475-476. doi:10.5114/dr.2022.126827. APA Maciejewska, M., Czuwara, J., Olszewska, & Rudnicka, (2022). Dermatologiczny, 109(6), 475-476. https://doi.org/10.5114/dr.2022.126827 Chicago Magda...

objective: multiple sclerosis (ms) is a chronic autoimmune disease due to demyelination of the central nervous system. it is believed that cytokines are involved in the pathogenesis of ms. the interleukin-2 (il2) gene is powerful functional candidate that is involved in immune regulation and operation. in this study, for the first time, we investigated the effect of -475 a/t and -631 g/a il2 po...

TAK-475 (lapaquistat acetate) and its active metabolite-I (TAK-475 M-I) inhibit squalene synthase, which catalyzes the conversion of farnesyl diphosphate (FPP) to squalene. FPP is a substrate for synthesis of other mevalonate-derived isoprenoids (MDIs) such as farnesol (FOH), geranlygeranyl diphosphate (GGPP), and geranylgeraniol. In patients with MKD, a rare autosomal recessive disorder, defec...

Correspondence to: 10 Darrin H. Brager, Ph.D. 11 Center for Learning and Memory 12 University of Texas at Austin 13 1 University Station, C7000 14 Austin, TX 78712–0805 15 512–475–7928 (voice) 16 512–475–8000 (fax) 17 [email protected] 18 19 Number of Figures: 4 20 Number of Pages: 22 21 Number of characters / words: 34938 / 5405 22 23 Articles in PresS. J Neurophysiol (August 21, 201...

The effects of feeding Fusarium moniliforme culture material, containing known concentrations of fumonisin Bj (FBi), were studied in turkey poults. Day-old poults were allotted randomly to dietary treatments containing 0, 0.41, 0.82, 1.23, 1.64, 2.87, 4.10, 5.33, 6.56, and 7.79% fumonisin culture material (FCM). These levels of FCM supplied 0, 25, 50, 75, 100, 175, 250, 325, 400, and 475 mg FBi...

We have evaluated the possibility that conserved cysteine residues are critical for the enzymatic function of p56lck. Through oligonucleotide-directed mutagenesis, 5 Lck residues (cysteines 217, 224, 378, 464, and 475) were individually mutated to alanines, and the effects of these substitutions were tested in various in vitro and in vivo assays. We found that mutation of either of 2 cysteines ...