After a three year interruption, we have decided to resume publication of the MDPI journal Pharmaceuticals (ISSN 1424-8247). This journal will henceforth publish papers on typical molecular medicines. In order to provide publishing services for those papers about topics which can be categorized as nutraceuticals or chemopreventives, we have set up a section in International Journal of Molecular...

Phoenix is a multi-agent planning system that fights simulated forest fires. In this paper we describe an experiment with Phoenix in which we uncover factors that affect the planner's behavior and test predictions about the planner's robustness against variations in some of these factors. We also introduct a technique – path analysis – for constructing and testing causal explanations of the pla...

Recent studies have provided strong evidence for the emergence of substantial numbers of constitutively active ESR1 mutations in estrogen-receptor positive metastatic breast cancer that are undetected in primary disease. Some of these mutants remain partially sensitive to current antiestrogen therapies but effective therapeutics targeted at them may require new approaches. Research. on April 14...