Abstract Introduction Mandibular advancement device (MAD) is designed to pull the mandible and tongue forward anteriorly increase cross-sectional airway dimension thus possibly reduce obstructions during sleep. The effectiveness of a MAD may be affected by pre-treatment OSA severity, BMI, degree changes in pharyngeal dimensions resulting from situ. In this study, 3D submental ultrasound imaging...

This paper considers the Pure Integer Capacitated Plant Location Problem (PI-CPLP). It is an NP-hard integer programming problem closely related to the Mixed Integer Capacitated Plant Location Problem (MI-CPLP). The di erence between the two lays in the integrality constraints on the assignment variables. As opposed to MI-CPLP, in PI-CPLP, for a given set of open plants, the assignment subprobl...

This paper establishes explicit quantitative bounds on the computation of approximate fixed points of asymptotically (quasi-) nonexpansive mappings f by means of iterative processes. Here f : C → C is a selfmapping of a convex subset C ⊆ X of a uniformly convex normed space X . We consider general Krasnoselski-Mann iterations with and without error terms. As a consequence of our quantitative an...

In [12], the second author obtained metatheorems for the extraction of effective (uniform) bounds from classical, prima facie nonconstructive proofs in functional analysis. These metatheorems for the first time cover general classes of structures like arbitrary metric, hyperbolic, CAT(0) and normed linear spaces and guarantee the independence of the bounds from parameters raging over metrically...

We have investigated the response of amino acid transport and protein synthesis in healthy elderly individuals (age 71+/-2 yr) to the stimulatory effect of increased amino acid availability. Muscle protein synthesis and breakdown, and amino acid transport were measured in the postabsorptive state and during the intravenous infusion of an amino acid mixture. Muscle-free amino acid kinetics were ...

Let 2 6 k1 < k2 < · · · < kt, 3 6 g1 < g2 < · · · < gs < N be integer parameters. A (k1, k2, . . . , kt; g1, g2, . . . , gs;N)-graph is a graph that contains vertices of degrees k1, k2, . . . , kt but no other degrees and cycles of lengths g1, g2, . . . , gs but no other cycles of length < N . For any given set of parameters satisfying the above conditions, we present an explicit construction o...

UNLABELLED All cancers contain an admixture of rapidly and slowly proliferating cancer cells. This proliferative heterogeneity complicates the diagnosis and treatment of patients with cancer because slow proliferators are hard to eradicate, can be difficult to detect, and may cause disease relapse sometimes years after apparently curative treatment. While clonal selection theory explains the pr...

Software Architecture modeling and representation is very important in software development process. Software Architecture provides high level view which is very useful in all phases of software life cycle. Component based software architecture is beneficial as it is useful for reusing system parts represented as components. Most of the existing object oriented systems do not have reliable soft...

ATP and UDP constrict rat intrapulmonary arteries, but which receptors mediate these actions is unclear. Here, we used selective agonists and antagonists, along with measurements of P2Y receptor expression, to characterize the receptor subtypes involved. Isometric tension was recorded from endothelium-denuded rat intrapulmonary artery rings (i.d. 200-500 μm) mounted on a wire myograph. Expressi...