نتایج جستجو برای: 1 dsm

تعداد نتایج: 2767474  

Journal: :The Journal of pharmacology and experimental therapeutics 2012
Shankar P Parajuli Rupal P Soder Kiril L Hristov Georgi V Petkov

Small conductance Ca²⁺-activated K⁺ (SK) and intermediate conductance Ca(2+)-activated K⁺ (IK) channels are thought to be involved in detrusor smooth muscle (DSM) excitability and contractility. Using naphtho[1,2-d]thiazol-2-ylamine (SKA-31), a novel and highly specific SK/IK channel activator, we investigated whether pharmacological activation of SK/IK channels reduced guinea pig DSM excitabil...

Journal: :Environmental toxicology 2016
Hung-En Liao Marthandam Asokan Shibu Wei-Wen Kuo Pei-Ying Pai Tsung-Jung Ho Chia-Hua Kuo Jing-Ying Lin Su-Ying Wen Vijaya Padma Viswanadha Chih-Yang Huang

Consumption of deep sea minerals (DSM), such as magnesium, calcium, and potassium, is known to reduce hypercholesterolemia-induced myocardial hypertrophy and cardiac-apoptosis and provide protection against cardiovascular diseases. Heart diseases develop as a lethal complication among diabetic patients usually due to hyperglycemia-induced cardiac-apoptosis that causes severe cardiac-damages, he...

Journal: :American journal of physiology. Renal physiology 2016
Wenkuan Xin Ning Li Vitor S Fernandes Biao Chen Eric S Rovner Georgi V Petkov

Large-conductance Ca(2+)-activated K(+) (BK) channels are critical regulators of detrusor smooth muscle (DSM) function. We aimed to investigate phosphodiesterase type 1 (PDE1) interactions with BK channels in human DSM to determine the mechanism by which PDE1 regulates human urinary bladder physiology. A combined electrophysiological, functional, and pharmacological approach was applied using h...

2014
Jennifer J Thomas Katherine A Koh Kamryn T Eddy Andrea S Hartmann Helen B Murray Mark J Gorman Stephanie Sogg Anne E Becker

BACKGROUND DSM-5 revisions have been criticized in the popular press for overpathologizing normative eating patterns-particularly among individuals with obesity. To evaluate the evidence for this and other DSM-5 critiques, we compared the point prevalence and interrater reliability of DSM-IV versus DSM-5 eating disorders (EDs) among adults seeking weight-loss treatment. METHOD Clinicians (n =...

2012
James Phillips Allen Frances Michael A Cerullo John Chardavoyne Hannah S Decker Michael B First Nassir Ghaemi Gary Greenberg Andrew C Hinderliter Warren A Kinghorn Steven G LoBello Elliott B Martin Aaron L Mishara Joel Paris Joseph M Pierre Ronald W Pies Harold A Pincus Douglas Porter Claire Pouncey Michael A Schwartz Thomas Szasz Jerome C Wakefield G Scott Waterman Owen Whooley Peter Zachar

In face of the multiple controversies surrounding the DSM process in general and the development of DSM-5 in particular, we have organized a discussion around what we consider six essential questions in further work on the DSM. The six questions involve: 1) the nature of a mental disorder; 2) the definition of mental disorder; 3) the issue of whether, in the current state of psychiatric science...

Journal: :Acta Psychiatrica Scandinavica 2016

Journal: :International journal of systematic and evolutionary microbiology 2002
A F W M Wolterink A B Jonker S W M Kengen A J M Stams

A Gram-negative, facultatively anaerobic, rod-shaped, dissimilatory chlorate-reducing bacterium, strain AW-1(T), was isolated from biomass of an anaerobic chlorate-reducing bioreactor. Phylogenetic analysis of the 16S rDNA sequence showed 100% sequence similarity to Pseudomonas stutzeri DSM 50227 and 98.6% sequence similarity to the type strain of P. stutzeri (DSM 5190(T)). The species P. stutz...

2008
Pablo d'Angelo Manfred Lehner Thomas Krauss Danielle Hoja Peter Reinartz

High resolution stereo satellite imagery is well suited for the creation of digital surface models (DSM). In this paper, a system for highly automated DSM and orthoimage generation based on CARTOSAT-1 imagery is presented. The proposed system processes photometrically corrected level-1 stereo scenes using the rational polynomial coefficients (RPC) universal sensor model. The RPC are derived fro...

Journal: :Alcohol and alcoholism 2008
Glenn D Walters

AIMS Archival data from structured interviews of 1193 male prison inmates were subjected to taxometric analysis to determine the latent structure of the alcohol use disorder construct. METHODS Analyses were performed using three taxometric procedures: mean above minus below a cut (MAMBAC), maximum eigenvalue (MAXEIG), and latent mode factor analysis (L-Mode). RESULTS The outcomes were based...

Journal: :بوم شناسی کشاورزی 0
محسن زعفرانیه جعفر ولی زاده سید مسعود ضیایی مجید جعفری محبوبه محسنی بابعبدانی

salinity is one of the environmental factors that have a critical influence on the plant emergence and plant growth and establishment. the determination of salinity tolerance threshold is a useful criterion to choose soil and irrigation water for cultivation of halophytes. in order to determine salinity tolerance threshold in amaranthus retrofelexus, an experiment was performed in greenhouse ba...

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