Impaired endothelial nitric oxide synthase (eNOS) function is associated with erectile dysfunction in diabetes mellitus, but the exact molecular basis for the eNOS defect in the diabetic penis remains unclear. We investigated whether hyperglycemia increases O-GlcNAc modification of eNOS in the penis, preventing phosphorylation at the primary positive regulatory site on the enzyme and hampering ...

Deep-space manned flight as a reality depends on a viable solution to the radiation problem. Both acute and chronic radiation health threats are known to exist, with solar particle events as an example of the former and galactic cosmic rays (GCR) of the latter. In this experiment Iron ions of 1A GeV are used to simulate GCR and to determine the secondary radiation field created as the GCR-like ...

Dioxins are a group of anthropogenic chemical compounds created as unintended by-products through a number of activities including: combustion, certain types of chemical manufacture, chlorine bleaching of pulp and paper, and other industrial processes. Dioxins are produced in very small quantities compared to other pollutants; however, because this family of compounds are thought to be highly t...

Ascent sequences were introduced by Bousquet-Mélou, Claesson, Dukes and Kitaev in their study of (2 + 2)-free posets. An ascent sequence of length n is a nonnegative integer sequence x = x1x2 . . . xn such that x1 = 0 and xi ≤ asc(x1x2 . . . xi−1) + 1 for all 1 < i ≤ n, where asc(x1x2 . . . xi−1) is the number of ascents in the sequence x1x2 . . . xi−1. We let An stand for the set of such seque...

Dublin Chester Beatty Kütüphanesi’nde Süryani koleksiyonunda Syc 703 numarada kayıtlı bulunan Harklean Dörtlü İncil el yazması makalenin konusunu oluşturmaktadır. El yazmasının şimdiye kadar detaylı monografik bir çalışmada incelenmediği ve yeteri bilinmediği görülmüştür. Bu nedenle eser kodikolojik, paleografik sanat-tarihsel yönden incelenmiş, sahip olduğu özellikleri tanıtılmaya çalışılmıştı...

Algebraic multigrid (AMG) is an efficient multilevel method for solving large sparse linear systems obtained from the discretisation of scalar elliptic partial differential equations. AMG can be used to compute powerful preconditioners for use with Krylov subspace methods. We report on the design and development of an efficient, robust and portable implementation of AMG that is available as pac...