0

The breast and ovarian cancer susceptibility gene BRCA1 contains an unusually high density (41.5%) of Alu elements. The homology between these repetitive Alu sequences can promote ectopic or homotopic homologous recombination. Ectopic homologous recombination, such as that reported in the BRCA1 gene, leads to large genomic rearrangements, which subsequently may cause disease phenotypes. In the ...

We construct twelve infinite families of pseudocyclic and non-amorphic association schemes, in which each nontrivial relation is a strongly regular graph. Three of the twelve families generalize the counterexamples to A. V. Ivanov’s conjecture by Ikuta and Munemasa [13].

tall fescue (lolium arundinaceum (schreb) sj darbysh.) is one of the fescue species that widely used as forage grass. tall fescue is self-incompatible and wind cross pollination. this study was conducted to study agronomic and morphological characteristics of 25 polycross families of tall fescue during 2011 and 2012 at research station farm in isfahan. number of days to pollination, height of p...

BACKGROUND Hypertrophic cardiomyopathy is a genetically heterogeneous myocardial disease with >1000 causal variants identified. Nonunique variants account for disease in many families. We sought to characterize nonunique variants in Australian families and determine whether they arise from common ancestral mutations or recurrent mutation events. METHODS AND RESULTS Genetic test results of 467...