نتایج جستجو برای: 149
تعداد نتایج: 11019 فیلتر نتایج به سال:
Lysosomes are sensitive to environmental stresses. Lysosomal membrane stability measured using lysosomal enzyme release assay (LERA) and expressed in terms of lysosomal lability index is employed as an early warning system for detection of disturbances in the surrounding environment. In the present study, lysosomal membrane stability of animals belonging to different phyla namely, Rattus norweg...
Methicillin-resistant Staphylococcus aureus (MRSA) burden is increasing worldwide in hospitals [healthcare-associated (HA)-MRSA] and in communities [community-associated (CA)-MRSA]. However, the impact of CA-MRSA within hospitals remains limited, particularly in Latin America. A countrywide representative survey of S. aureus infections was performed in Argentina by analyzing 591 clinical isolat...
Crystal structures of complexes of a D30N mutant of feline immunodeficiency virus protease (FIV PR) complexed with a statine-based inhibitor (LP-149), as well as with a substrate based on a modification of this inhibitor (LP-149S), have been solved and refined at resolutions of 2.0 and 1.85 A, respectively. Both the inhibitor and the substrate are bound in the active site of the mutant protease...
BACKGROUND Patients with Parkinson's disease (PD) have different cognitive impairments. The goal of this study is the analysis of these changes in the mentioned patients. METHODS A cross-sectional study was performed on 87 patients with PD. Patients were given a questionnaire to gather data about their medical and living statuses. To assess cognitive assessment, SCOPA-COG (Scales for Outcome ...
microRNAs have been implicated in hepatocellular carcinoma (HCC) metastasis, which is predominant cause of high mortality in these patients. Although an increasing body of evidence indicates that miR-149 plays an important role in the growth and metastasis of multiple types of cancers, its role in the progression of HCC remains unknown. Here, we demonstrated that miR-149 was significantly down-...
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