The methodology described in this article was developed to transcend the limitations of both approaches. Its goal is to use existing data to identify small areas with high levels of adolescent childbearing. The method is an active approach to identify what can be defined as “hot spots” for adolescent births, even when they are located in counties or communities where adolescent births are not c...

Tooth root formation is initiated by the elongation of Hertwig’s epithelial root sheath (HERS). HERS cells are widely accepted to control root formation, but the mechanisms regulating HERS growth have not been elucidated. To solve this problem, we have established a new culture method for postnatal mouse mandibular molars and, using it, examined the role of insulin-like growth factor-I (IGF-I) ...

RAPID EYE MOVEMENT (REM) SLEEP BEHAVIOR DISORDER (RBD) IS A PARASOMNIA CHARACTERIZED BY DREAM-ENACTING BEHAVIORS RELATED TO LOSS OF the normal generalized skeletal muscle atonia during REM sleep1,2. RBD may be idiopathic or associated with neurodegenerative diseases such as Parkinson’s disease3, multiple system atrophy4, dementia with Lewy bodies5, Machado-Joseph disease6 and parkinsonism with ...

host defenses allow varying types of infection. Candidal infections offer a clear example of this point. Granulocytes primarily prevent bloodborne candidiasis, and this becomes apparent in neutropenic patients, who are at greater risk to develop Candida-induced fungemia and sepsis. Contrast this situation with the T-cell–mediated defense that prevents mucosal Candida proliferation. This propert...

In this study, we investigate the relationship between uncertainty and trust in exogenous shifts in modes of social exchange (i.e., those that are not initiated by the individuals in a given exchange system). We explore how transitions from a high uncertainty environment (reciprocal exchange) to lower-uncertainty environments (nonbinding or binding negotiated exchange) affect the level of trust...

Maize (Zea mays L.) is a host to numerous pathogenic species that impose serious diseases to its ear and foliage, negatively affecting the yield and the quality of the maize crop. A considerable amount of research has been carried out to elucidate mechanisms of maize-pathogen interactions with a major goal to identify defense-associated proteins. In this review, we summarize interactions of mai...

been a lightning rod for opponents. Title X funds are distributed directly by the federal government to a range of grantees, which include state agencies as well as nonprofit organizations such as Planned Parenthood affiliates and regional family planning councils. Title X funds are distributed in all states. Two major federal block grants, the maternal and child health (MCH) and the social ser...

The resurgence of Chikungunya virus (CHIKV) in the southern, northeastern and northern parts of Thailand, inflicting approximately 46,000 reported cases since October 2008 until December 2009, has raised public health concerns. In the present study, we characterized nearly complete genome sequences of four CHIKV isolates obtained from 2008 to 2009 outbreaks in Thailand. Phylogenetic analysis wa...

it decreased from 96 to 93 per 1,000 among whites.3 Minority adolescents are disproportionately represented among teenagers who give birth; of the 38 states that reported rates for 1991–1992, 27 reported an increase in birthrates among Hispanic adolescents, whereas only six of 50 states reported an increase in birthrates among non-Hispanic white teenagers.4 Although no research has been conduct...

Sea-blue histiyositoz Niemann-Pick hastalığının altı tipinden biridir. Çocukluk çağında başlayan hepatosplenomegali olması, nörolojik tutulumun olmaması ve sfingomiyelinaz aktivitesinin azalmasıyla karakterizedir. Akciğer tutulumu sea-blue histiyositozda görülen nadir bir klinik tutulumdur. Bu olgu sunumunda, 15 yaşındayken sea-blue histiyositoz tanısı konulan 39 yaşındaki bir erkek hasta sunul...