نتایج جستجو برای: 1775 mjm

تعداد نتایج: 1555  

Journal: :international journal of energy and environmental engineering 2011
sunday olayinka

in this study, estimation of global and diffuse solar radiations of selected cities in nigeria was carried out to assess the feasibility of solar energy utilization. the results of this work show the variation of direct and diffuse component of solar radiation in summer and winter months. the contribution of diffuse solar radiation is high during the monsoon months whereas sky conditions are cl...

Journal: :McGill Journal of Medicine 2020

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2015
Noriaki Tanaka Ameeta A Patel Jiping Wang Mitchell J Frederick Nene N Kalu Mei Zhao Alison L Fitzgerald Tong-xin Xie Natalie L Silver Carlos Caulin Ge Zhou Heath D Skinner Faye M Johnson Jeffrey N Myers Abdullah A Osman

PURPOSE Although the majority of patients with HPV(+) oropharyngeal cancers have a favorable prognosis, there are some patients with tumors that are resistant to aggressive chemoradiotherapy with unusual patterns of locoregional and systemic recurrences. Therefore, more effective therapies are needed. In this study, we investigated the chemosensitizing efficacy of the selective Wee-1 kinase inh...

2011
Kathleen A. Bridges Hiroshi Hirai Carolyn A. Buser Colin Brooks Huifeng Liu Thomas A. Buchholz Jessica M. Molkentine Kathryn A. Mason Raymond E. Meyn

Purpose: Radiotherapy is commonly used to treat a variety of solid tumors. However, improvements in the therapeutic ratio for several disease sites are sorely needed, leading us to assess molecularly targeted therapeutics as radiosensitizers. The aim of this study was to assess the wee1 kinase inhibitor, MK-1775, for its ability to radiosensitize human tumor cells. Experimental Design: Human tu...

2011
Bhaswati Sarcar Soumen Kahali Antony H. Prabhu Stuart D. Shumway Yang Xu Prakash Chinnaiyan

Thepurpose of this studywas todetermine the capacity ofMK-1775, apotentWee-1 inhibitor, to abrogate the radiation-induced G2 checkpoint arrest andmodulate radiosensitivity in glioblastoma cell models and normal human astrocytes. The radiation-induced checkpoint response of established glioblastoma cell lines, glioblastoma neural stem (GNS) cells, and astrocytes were determined in vitro by flow ...

Journal: :Neuro-oncology 2014
Sabine Mueller Rintaro Hashizume Xiaodong Yang Ilan Kolkowitz Aleksandra K Olow Joanna Phillips Ivan Smirnov Maxwell W Tom Michael D Prados C David James Mitchel S Berger Nalin Gupta Daphne A Haas-Kogan

BACKGROUND We investigated the efficacy of the Wee1 inhibitor MK-1775 in combination with radiation for the treatment of pediatric high-grade gliomas (HGGs), including diffuse intrinsic pontine gliomas (DIPGs). METHODS Gene expression analysis was performed for 38 primary pediatric gliomas (3 grade I, 10 grade II, 11 grade III, 14 grade IV) and 8 normal brain samples using the Agilent 4 × 44 ...

Journal: :iranian journal of animal biosystematics 0
seyfabadi m.m. zamani jamshidi a. mahvary-habibabadi

the hermit crab fauna of the larak island was investigated, which revealed seven species representing five genera and two families. the family diogenidae represents six species namely areopaguristes perspicax (nobili, 1906), clibanarius signatus heller, 1861, dardanus lagopodes (forskål, 1775), d. tinctor (forskål, 1775), d. avarus heller, 1865, d. tirmiziae siddiqui & mclaughlin, 2003, while t...

2018
Małgorzata M. Michalska-Jakubus Katarzyna Zdeb Beata Rymgayłło-Jankowska Agnieszka Korolczuk Tomasz Żarnowski Dorota Krasowska

Address for correspondence: Małgorzata M. Michalska-Jakubus, Department of Dermatology, Venereology and Paediatric Dermatology, Medical University of Lublin, 13 Radziwiłłowska St, 20-080 Lublin, Poland, phone: +48 693 549 654, e-mail: [email protected] Received: 4.02.2016, accepted: 10.08.2017. Occupational exposure as a presumable cause of subcutaneous sarcoidosis in a tannery worker – case r...

2016
Dandan Zhang Jinwei Li

A checklist of the 31 Chinese species of Udea is given, including the new species and new records. Udea curvata sp. n. and Udea albostriata sp. n. are described and illustrated. Udea exigualis (Wileman, 1911), Udea stationalis Yamanaka, 1988, Udea prunalis (Denis & Schiffermüller, 1775), Udea elutalis (Denis & Schiffermüller, 1775) and Udea cyanalis (La Harpe, 1855) are newly recorded for China.

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