Aberrantly expressed microRNAs contribute to the initiation and progression of human cancers. However, the underlying functions of microRNA-187 (miR-187) in colorectal cancer (CRC) remain largely unexplored. Here, we demonstrated that miR-187 was significantly down-regulated in CRC tissues and cell lines compared to their normal counterparts. By Kaplan-Meier analysis, we revealed that decreased...

The authors present a simple classroom experiment that can be used as a teaching device to introduce important concepts of organizational economics and incentive contracting. First, students take the role of a principal and design a contract that consists of a fixed payment and an incentive component. Second, students take the role of agents and decide on an effort level. The experiment illustr...

This study was undertaken in order to identify and describe the nature of socialization of females into sport. A fixed-alternative questionnaire was administered to 585 women who were currently active in sport. Results indicated that peers and family were the significant agents of socialization during childhood, peers and school were aost significant during adolescence, and peers were most sign...

The cyclotron frequency ratio of $^{187}\mathrm{Os}^{29+}$ to $^{187}\mathrm{Re}^{29+}$ ions was measured with the Penning-trap mass spectrometer PENTATRAP. achieved result $R=1.000\:000\:013\:882(5)$ is date most precise such measurement performed on ions. Furthermore, total binding-energy difference 29 missing electrons in Re and Os calculated by relativistic multiconfiguration methods, yield...

L’auteur évoque librement des liens conceptuels entre les travaux de Sami-Ali et ceux deux penseurs la postmodernité, à savoir Michel Foucault Gilles Deleuze, travers notions « dispositif », « territorialisation », « jeu idéal », d’« ubiquité instantanéité » «&#160...

The aldolase catalytic cycle consists of a number of proton transfers that interconvert covalent enzyme intermediates. Glu-187 is a conserved amino acid that is located in the mammalian fructose-1,6-bisphosphate aldolase active site. Its central location, within hydrogen bonding distance of three other conserved active site residues: Lys-146, Glu-189, and Schiff base-forming Lys-229, makes it a...

Los distintos sectores –educativo, medico, laboral, empresarial, económico, social, comunicacional y cultural– entre otros, han mediatizado gran parte de sus procesos ejecución.

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