K. Almond*, P. Bikker, M. Lomax, M. E. Symonds and A. Mostyn Academic Division of Child Health, School of Clinical Sciences, E floor East Block, University Hospital, Nottingham NG7 2UH, UK Division of Nutritional Sciences, School of Biosciences, North Lab, University of Nottingham, Sutton Bonnington Campus, Loughborough LE12 5RD, UK Schothorst Feed Research, Lelystad, The Netherlands School of ...

The in vitro activities of temafloxacin (A63004) and lomefloxacin (SC-47111; NY-198) were compared with those of seven other antibiotics against 146 isolates of bacterial enteric pathogens, including Campylobacter jejuni and Campylobacter coli. Ciprofloxacin was the most active drug against the Salmonella, Shigella, Yersinia, and Vibrio spp. tested. Lomefloxacin, temafloxacin, and difloxacin we...

The earth’s environments and ecosystems are not fi xed but vary over a wide range of space and time scales (Delcourt, and Webb 1982; see also fi g. 6.1). At the scale of tens of thousands of years, the wobble of the Earth on its axis causes variation in the solar radiation received at the earth’s surface, driving variation in climate. On shorter time scales, the Southern Oscillation of sea surf...

The regulation of gene transcription involves a dynamic balance between packaging regulatory sequences into chromatin and allowing transcriptional regulators access to these sequences. Access is restricted by the nucleosomes, but these can be repositioned or ejected by enzymes known as nucleosome remodellers. In addition, the DNA sequence can impart stiffness or curvature to the DNA, thereby af...

UNLABELLED Hearing loss in the elderly is one of the most frequent chronic diseases. AIM to estimate the prevalence of hearing loss in a representative sample of elderly people (aged 65 or over) in the city of Rio de Janeiro. MATERIAL AND METHOD a prospective, cross-sectional population-based study with 238 elderly people aged 65 years or more (198 women and 40 men). RESULTS the prevalenc...

Results HCM patients (50±18 years, 65% men) had normal LVEDV (149±46mL, p=0.24), LVESV (52±24mL, p=0.78) and LVEF (65±11%, p=0.38). LV mass (198±69g, p<0.001) and LV mass index (108±37g/m2 p=0.002) were significantly increased, resulting in decreased LV mass/LV volume ratio (1.40±0.54, p=0.005) in HCM compared to controls. Median maximal wall thickness was 19.6 (14.4 to 32.3mm). In HCM, LGE was...