Natural killer cells derived from pluripotent hematopoietic stem cells are important cells of the immune system that have two main functions: a cytolytic activity and a cytokine-producing capacity. These functions are tightly regulated by numerous activating and inhibitory receptors, including newly discovered receptors that selectively trigger the cytolytic activity in a major histocompatibili...

aids over 100 years ago, the search has been on for a way to fully compensate for all aspects of hearing impairment by hearing aid amplification. To date, this goal has not been achieved. However, as hearing aid technology has developed from the era of carbon aids to the present-day digital signal processors, much progress has been made in making optimal use of the available technology. The vas...

Proper mechanical and electrical coupling of cardiomyocytes is crucial for normal propagation of the electrical impulse throughout the working myocardium.Various proteins on the surface of cardiomyocytes are responsible for the integration of structural information and cell-cell communication. Increasing evidence from diseased myocardium and animal models indicates that alteration in electrical...

Diagnostic accuracy of the currently available serum markers of cardiac injury, such as myoglobin, creatine kinase and its myocardial isoform, are altered in patients with renal failure. It is shown that cardiac troponins have decreased diagnostic sensitivity and specificity in patients receiving renal replacement therapy. Data regarding serum levels of these cardiac biomarkers, especially thos...

CONTENTS 1. McMullin on revolutions Initial statement. McMullin's challenges McMullin's own epistemology: retroduction My own question for Ernan 2. Empiricism vs Metaphysics Initial statement. Impossibility of a thesis driven critique Critique indeed value-driven, in part How can a stance provide an effective critique? Jauernig: the values involved Analogy to a moral stance How does this apply ...