Functionalizing metal-organic frameworks (MOFs) with amines is a commonly used strategy to enhance their performance in CO2 capture applications. As such, this work, two-step covalently functionalize NH2-containing MOFs short chain polyamines was developed. In the first step, parent MOF, Zn4O(NH2-BDC)3, exposed bromoacetyl bromide (BrAcBr), which readily reacts pendant -NH2 groups on 2-amino-1,...

A review of computational methodsfor miRNA target prediction

miR-218, consisting of miR-218-1 at 4p15.31 and miR-218-2 at 5q35.1, was significantly decreased in esophageal squamous cell carcinoma (ESCC) in our previous study. The aim of this study was to determine whether aberrant methylation is associated with miR-218 repression. Bisulfite sequencing analysis (BSP), methylation specific PCR (MSP), and 5-aza-2'-deoxycytidine treatment assay were applied ...

With the aim to find suitable hydrogen storage materials for stationary and mobile applications, multi-cation amide-based systems have attracted considerable attention, due their unique hydrogenation kinetics. In this work, AmZn(NH2)n (with A = Li, K, Na, Rb) were synthesized via an ammonothermal method. The phases mixed ball milling with LiH form AmZn(NH2)n-2nLiH m 2, 4 n 4, 6), as well Na2Zn(...

We previously reported frequent loss of microRNA‑218 (miR‑218) in human cervical cancer, which was associated with tumor progression and poor prognosis. In this study, we investigated whether restoration of the miR‑218 level is a valid strategy for the treatment of cervical cancer. The expression of miR‑218 in cervical cancer samples and cell lines was quantified by reverse transcription TaqMan...

PURPOSE To investigate the regulatory mechanism of miR-218 in human hepatocellular carcinoma (HCC). METHODS qPCR was used to compare the expression levels miR-218 among six hepatocellular carcinoma cell lines and normal liver tissues. After transfecting MHCC97L cells with either miR-218 mimics or miR-218 inhibitor, western blotting was used to examine the expressing patterns of cyclinD1, p21,...