نتایج جستجو برای: 254
تعداد نتایج: 7177 فیلتر نتایج به سال:
The altered metabolism in most tumor cells consists of elevated glucose uptake and increased glycolysis even in the presence of high oxygen tension. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is an obligatory enzyme in glycolysis. Here, we report that acetylation at lysine 254 (K254) increases GAPDH activity in response to glucose. Furthermore, acetylation of GAPDH (K254) is reversibly re...
253 Use of Transfer Factor in Patients with Persistent Genital Human Papillomavirus Infection Blanca Maria Morfin-Maciel, MD, and Julieta Margarita Sotelo-Ortiz. Allergy, Hospital Angeles Mocel, Mexico City, Mexico; Gynecology, Hospital Angeles Mocel, Mexico City, Mexico. Background: Human papillomavirus (HPV) is the most common sexually transmitted infection worldwide. About 75 to 80% of sexua...
We describe a reversed-phase HPLC method for determination of total mycophenolic acid (MPA), its free concentration (MPAf), and the glucuronide metabolite (MPAG), based on simple sample preparation and gradient elution chromatography. The compounds were quantified in parallel by absorbance at 254 nm and 215 nm in the internal standard mode. Linearity was verified up to 50 mg/L for MPA and up to...
MAGE-encoded antigens, which are expressed by tumors of many histological types but not in normal tissues, are suitable candidates for vaccine-based immunotherapy of cancers. Thus far, however, T-cell responses to MAGE antigens have been detected only occasionally in cancer patients. In contrast, by using HLA/peptide fluorescent tetramers, we have observed recently that CD8(+) T cells specific ...
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