A 45-year-old Japanese woman with a bulky (75 x 40 mm) stage 2a uterine cervical cancer was treated with 87 mg (50 mg/m2) of nedaplatin (254-S) intravenously and 120 mg (70 mg/m2) of cisplatin (CDDP) intraarterially with transcatheter arterial embolization (TAE). She received three courses of this combination chemotherapy and showed a complete response, as confirmed by magnetic resonance imagin...

www.mathworks.com The purpose of RTCA/DO-254 (referred to herein as “DO-254”) is to provide guidance for the development of airborne electronic hardware. The Federal Aviation Administration (FAA), European Aviation Safety Agency (EASA), and other worldwide aviation safety authorities require this standard to ensure that complex electronic hardware used in aircraft systems works as specified und...

background: contagion of aquatic ecosystems to heavy metals especially mercury (hg) has risen concerns about healthiness of marine organisms. organic mercury compounds are highly toxic for animals, and its detection in various samples is frequently needed. in present study we have described a new method for measurement of organic mercury and total mercury concentration in great cormorants (phal...

This paper introduces a framework to produce and to manage quality requirements of embedded aeronautical systems, called the ‘Requirements Engineering Framework’ (REF). It aims at making the management of the requirement lifecycle easier, from the specification of the purchaser’s needs, to their implementation in the final products, and also their verification, while controlling costs. REF is b...

T h i s r epor t documents the f e a s i b i l i t y s tudy d o n e a t S t a n f o r d U n i v e r s i t y ’ s A r t i f i c i a l I n t e l l i g e n c e L a b o r a t o r y o n t h e p r o b l e m o f c o m p u t e r a u t o m a t e d a e r i a l / o r b i t a l p h o t o g r a m m e t r y . T h e t e c h n i q u e s i n v e s t i g a t e d w e r e b a s e d o n c o r r e l a t i o n m a t c...

The altered metabolism in most tumor cells consists of elevated glucose uptake and increased glycolysis even in the presence of high oxygen tension. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is an obligatory enzyme in glycolysis. Here, we report that acetylation at lysine 254 (K254) increases GAPDH activity in response to glucose. Furthermore, acetylation of GAPDH (K254) is reversibly re...