One hectare of tropical dry forest in Guanacaste Conservation Area, Cosra Rica was mapped and all trees larger than 10 cm diameter at breast heighr (DBH) identified. The same hectare was sampled for leaf litter and the two data sets, forest and litter, were compared. Dominant and subdominant species of the forest are represented in the leaf litter, whereas rare tree species are highly variable ...

CD8(+) T lymphocytes (T(CD8)) responding to subdominant epitopes provide alternate targets for the immunotherapy of cancer, particularly when self-tolerance limits the response to immunodominant epitopes. However, the mechanisms that promote T(CD8) subdominance to tumor Ags remain obscure. We investigated the basis for the lack of priming against a subdominant tumor epitope following immunizati...

Question: In the same landscape context – at a desert grassland-shrubland transition zone, how does subdominant plant abundance vary in microsites around dominant grasses and shrubs? Location: Sevilleta LTER, New Mexico, USA (34°21' N; 106°53' W; 1650 m a.s.l.). Methods: We compared the distribution of subdominant plants in canopy, canopy edge and interspace microsites around individual shrubs ...

Pollution of the environment by human and animal faecal pollution affects the safety of shellfish, drinking water and recreational beaches. To pinpoint the origin of contaminations, it is essential to define the differences between human microbiota and that of farm animals. A strategy based on real-time quantitative PCR (qPCR) assays was therefore developed and applied to compare the compositio...

CD8(+) T cell responses are critical for the control of virus infections. Following infection, epitope-specific responses establish an unpredictable but reproducible pattern of dominance that is dictated by a large number of both positive and negative factors. Immunodomination, or diminution of subdominant epitope-specific responses by dominant epitopes, can play a substantial role in the estab...

UNLABELLED The composition of the human intestinal microbiota is linked to health status. The aim was to analyze the microbiota of normal and colon cancer patients in order to establish cancer-related dysbiosis. PATIENTS AND METHODS Stool bacterial DNA was extracted prior to colonoscopy from 179 patients: 60 with colorectal cancer, and 119 with normal colonoscopy. Bacterial genes obtained by ...

From numerical solutions of a gyrokinetic model for ion temperature gradient turbulence it is shown that nonlinear coupling is dominated by three-wave interactions that include spectral components of the zonal flow and damped subdominant modes. Zonal flows dissipate very little energy injected by the instability, but facilitate its transfer from the unstable mode to dissipative subdominant mode...

Rapidly evolving pathogens such as HIV or influenza can quickly mutate their antigenic profiles, reducing the efficacy of conventional vaccines. Despite this challenge, functionally required epitopes are highly conserved among heterologous viral strains and represent a key vulnerability that could be targeted during vaccine development. As the antigenicity of these conserved epitopes is frequen...

Many of the factors that contribute to CD8+ T cell immunodominance hierarchies during viral infection are known. However, the functional differences that exist between dominant and subdominant epitope-specific CD8+ T cells remain poorly understood. In this study, we characterized the phenotypic and functional differences between dominant and subdominant simian immunodeficiency virus (SIV) epito...