What does a horticulturist or landscape architect strive to attain when choosing plants for a naturalistic animal exhibit in any major zoo? Should visitors come upon bananas and tropical figs complementing an exhibit featuring giraffes or zebras that naturally roam the hot, arid Serengeti? Let’s hope not. Likewise, they should not be confronted by trees that resemble the acacias of arid Kenya a...

The National Cancer Institute (NCI) and the National Toxicology Program (NTP) have carried out a number of laboratory animal carcinogenicity studies and presented the results of these experiments in a series of Technical Reports. This paper tabulates the results of the 327 NCI/NTP studies carried out to date on 308 distinct chemicals, and discusses certain issues relevant to the evaluation of c...

Although there are several lines of evidence regarding the prehistoric spread of farming peoples through the forest, nothing is known about the original pygmy occupation, nor the evolution of their relationship with the horticulturists. This paper will examine the history, geography, and ecology of that forest, and the prehistoric immigration of farming peoples in order to provide a context for...

A nonsense allele of the yeast RAD52 gene, rad52-327, which expresses the N-terminal 65% of the protein was compared to two missense alleles, rad52-1 and rad52-2, and to a deletion allele. While the rad52-1 and the deletion mutants have severe defects in DNA repair, recombination and sporulation, the rad52-327 and rad52-2 mutants retain either partial or complete capabilities in repair and reco...

11.4 Caves and Other Subterranean Sites .......................... 327 11.4.1 The Cave Environment .................................................... 327 11.4.2 Light ................................................................................ 330 11.4.3 The Organisms and Their Response to the Environment .......................................................... 332 11.4.4 Calci fi catio...

MicroRNA (miRNA/miR) dysregulation has been reported to be fundamental in the development and progression of cardiac hypertrophy and fibrosis. In the present study, miR-327 levels in fibroblasts were increased in response to cardiac hypertrophy induced by transverse aortic constriction with prominent cardiac fibrosis, particularly when compared with the levels in unstressed cardiomyocytes. In n...