BACKGROUND Radiation resistance poses a major clinical challenge in treatment of esophageal squamous cell carcinoma (ESCC). However, the mechanisms of radioresistance has not been fully elucidated. Since accumulating evidence demonstrates that aberrant expression of microRNAs (miRNAs) contributes to cancer sensitivity to radiation, we aimed to identify miRNAs associated with radioresistance of ...

Introduction Epidemiologic studies suggest that joint bleeding occurs in patients with mild-to-moderate haemophilia, including women and girls. However, most previous on the impacts of haemophilia focus men severe disease. Aim To identify unmet needs haemophilia. Methods The Pain, Functional Impairment, Quality Life (P-FiQ) study assessed impact pain functional impairment health-related quality...

Social trust is the main component of social capital. In this regard, subjective welfare is one of the important aspects of human life. Based on the human needs growth, it must be considered both objective and subjective aspect of welfare. The present study tries to use survey method and collect data by cluster sampling among 381 persons of 20-29 Youth in Tehran as the sample of this research. ...

The lack of accurate population-based information on childhood cancer stage and survival in low-income countries is a barrier to improving outcomes. In our study, data from three registries sub-Saharan Africa (Abidjan, Harare Kampala) were examined for children aged under 15. We assessed the feasibility assigning at diagnosis according Tier 1 Toronto Childhood Cancer Stage Guidelines patients w...

Glioma is the most frequent primary intracranial tumor worldwide. Dexmedetomidine an efficient anesthetic used in surgery and has impact on glioma. Yet, mechanism of dexmedetomidine biological characteristics glioma cells unknown. Circ_BRAF, microRNA-381-3p thrombospondin 2 was detected via quantitative reverse transcription-polymer chine reaction. Proliferation detection conducted using 3-(4,5...

School of Marilia, São Paulo, Brazil; Flow Citometry, and; Dermatology, Medical School of Marilia, Marilia, Brazil. Background: The prevalence of hypersensitivity to nonsteroidal anti-inflammatory drugs (NSAIDs) is high and its in vitro diagnostic is a challenge. The basophil activation test with determination by flow cytometry (FC), of the expression rate of CD63 molecules has been much studie...

A survey was conducted in the northern district of Yamaguchi, Japan to determine the relationship between neurological diving accidents and risk factors among commercial breath-hold divers (Ama). A questionnaire was distributed to 381 Ama divers who are members of the Ama diving union. We sought information on their dive practices (depth of single dive, single dive time, surface interval, lengt...