نتایج جستجو برای: 3ms

تعداد نتایج: 175  

Journal: :JAMA internal medicine 2013
Frank R Lin Kristine Yaffe Jin Xia Qian-Li Xue Tamara B Harris Elizabeth Purchase-Helzner Suzanne Satterfield Hilsa N Ayonayon Luigi Ferrucci Eleanor M Simonsick

BACKGROUND Whether hearing loss is independently associated with accelerated cognitive decline in older adults is unknown. METHODS We studied 1984 older adults (mean age, 77.4 years) enrolled in the Health ABC Study, a prospective observational study begun in 1997-1998. Our baseline cohort consisted of participants without prevalent cognitive impairment (Modified Mini-Mental State Examination [...

Journal: :JAMA 2011
Kristine Yaffe Andrea Weston Neill R Graff-Radford Suzanne Satterfield Eleanor M Simonsick Steven G Younkin Linda H Younkin Lewis Kuller Hilsa N Ayonayon Jingzhong Ding Tamara B Harris

CONTEXT Lower plasma β-amyloid 42 and 42/40 levels have been associated with incident dementia, but results are conflicting and few have investigated cognitive decline among elders without dementia. OBJECTIVE To determine if plasma β-amyloid is associated with cognitive decline and if this association is modified by measures of cognitive reserve. DESIGN, SETTING, AND PARTICIPANTS We studied...

Journal: :The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 2012
Catherine Lacny Andrew Kirk Debra G Morgan Chandima Karunanayake

OBJECTIVE Patients with dementia benefit from early assessment and diagnosis. In an attempt to identify factors leading to delay in referral, we investigated socio-demographic, clinical, and functional predictors of greater severity of cognitive impairment in dementia patients presenting to a memory clinic in Saskatoon, Saskatchewan. METHODS Data collection began in 2004 at the Rural and Remo...

Journal: :Journal of Applied Fluid Mechanics 2023

The formation of supercavitation after a high-speed projectile enters water has decisive impact on the underwater ballistic and penetration projectile. In this study, Ansysfluent19.0 simulation software is used to study entry chosen at velocities 300, 400, 500, 600 m/s. cavitation characteristics, trajectories, flow-field characteristics are analyzed for 5.8-mm caliber conical flat head project...

Journal: :Frontiers in Marine Science 2022

Coastal wetlands are considered as important “blue carbon” sink, and mowing management induced by anthropogenic activities is anticipated to profoundly affect soil carbon stocks in coastal wetlands. However, the impacts of on organic (SOC) enzyme mechanisms responsible for associated changes Phragmites australis wetland remain uncertain. We conducted a field manipulation experiment [control (CK...

Journal: :dental research journal 0
sham kishor kanneppady balamanikanda srinivasan ramesh kumaresan santosh b. sakri

background: the patterns of facial growth, jaw and tooth size are inherited and are likely to differ among population and races. aim of this study is to evaluate and compare the pattern of third molar (3m) impaction among three different ethnic groups (chinese, indian, malay) of patients attending aimst dental institute, malaysia. materials and methods: dental records and orthopantomographs of ...

Journal: :Nephrology nursing journal : journal of the American Nephrology Nurses' Association 2008
Debra J Hain

As the number of older adults undergoing hemodialysis increases, it is important for nurses to consider cognitive impairment as a contributing factor to non-adherence. The purpose of this exploratory study was to identify cognitive markers that nurses can use to alert them to potential problems with adherence among older adults undergoing hemodialysis. Stories of the health challenge of making ...

2014
Judith Seary Philip St. John Suzanne Tyas Khalid Almulla Howard Chertkow Johanne Monette Susan Gold Geva Maimon Karen Leung Doreen Rabi Duyen Nguyen Sonia Butalia Jean Chabot Gary Inglis Syed Al Raza Naqvi Sehrish Haider Shabbir Alibhai Jennifer Watt Lizebeth Cox Richard Crilly Jacqueline McMillan Jayna Holroyd-Leduc Nathalie Jette Wendy Wong Bonnie Dobbs Diane McNeil Anita Saini Bonnie Dobbs Michelle Jessop Ling Zi Mu Jasneet Parmar Rhianne McKay Shirley Samuel-Haynes Oksana Babenko Joelle Bradley Leslie Rodgers David Ryan Manveen Puri Barbara Liu Jed Shimizu Jim Raso Debra Paches Douglas Lam Grace Maier Sandra Holowaty Edmond Lou Isabel Henderson Wonita Janzen Kenneth Warren Sharon Warren Marc Saint-Martin Claire Allen Sandy MacLean Jasneet Parmar Ekaterina Dolganova Chris Frank Cheryl Sadowski Carlos Rojas-Fernandez Corey Tsang Natalie Ward Barbara Farrell Lisa Pizzola Anne Holbrook Marie Leung Christopher Frank Michelle Gibson Peng You Joseph Lindsay Alex Kuo Michael Borrie Ali Hamou Femida Gwadry-Sridhar Jain Rahul Jocelyn Charles Annie Hadi Debbie Elman Jennifer Kong Carlie Scharf Cheryl Sadowski Ambikaipakan Senthilselvan Kannayiram Alagiakrishnan Karen Leung Haley Abrams Shakibeh Edani Michael La Michael Allan Stephanie Siu Janet Pope Katalin Balogh Jenny Basran Samuel Alan Stewart Heather Ward Ada Lam Caleb Yeung Verena Menec Philip D. St. John Suzanne L. Tyas Genevieve Courteau Godmaire Sébastien Grenier Cara Tannenbaum Victoria Xu Shelly Veinish Jurgis Karuza Paul Katz Gary Naglie Shafagh Fallah Anna Berall Yoel Green Isabelle Assouline Nancy Mayo Suzanne N. Morin Maral Koolian Jean-Marc Troquet Maryse Godin Michelle Wall Edmond Lou Connie Luu Sujin Kim Christine Hughes Sarah Goodwin-Woolmore Michael Borrie Frank Molnar Jose Morais Katelyn Fraser George Heckman Richard Hughson Mei Huang Lisa Koski Elyse Gordon Susan Muir-Hunter Mark Speechley Manuel Montero-Odasso Maya Bystrzycki Silvia Duong Cara Tannenbaum Philippe Martin Andrea Benedetti Robyn Tamblyn Cara Tannenbaum Sara Ahmed Ken Madden Jocelyn Chase Karen Gopaul Manuel Montero-Odasso Olivier Beauchet Mark Speechley Afua Oteng-Amoako Susan Hunter Cedric Annweiler Xiaowei Song Kenneth Rockwood Arnold Mitnitski Xiaowei Song Arnold Mitnitski Zhenhui Guo Jian Liu An Zeng Jiahui Dong Kenneth Rockwood Jean Triscott Earle Waugh Roger Parent Susan Chadoir Olga Szafran Alexandra Marin Shelly Veats Leslie Charles Jillian Alston Breanne Paul Doris Milke James Leask Courtney Kennedy Suzanne Morin Mary-Lou van der Hors Robert Josse Lisa Dolovich Richard Crilly Lynne Lohfeld Carly Skidmore Lehana Thabane Anna Sawka Lora Giangregorio Glenda Campbell Ravi Jain Laura Pickard George Ioannidis Lynn Nash Johnathan Adachi Alexander Papaioannou Sharon Marr Jackie Stroud Angela Juby Christopher Davis David Hanley Marilyn Cree Camilla Wong Robert Sargeant Maria Zorzitto Samir Sinha Mireille Norris Matthew Cor Karen Chan Lesley Charles Rhianne McKay Bonnie Dobbs Camilla Wong Raghda Alatia Yeo (Holly) Lee Sharon Straus Amanda McFarlan Jodeme Goldhar Gabriel Chan Dipti Purbhoo Yvonne Ashford Andrea Gruneir Sid Feldman Linda Jackson Barbara Liu Lesley Charles Bonnie Bobbs Oksana Babenko Jean Triscott

Methods: In 1991, 1763 community-dwelling adults aged 65+ participated in the Manitoba Study of Health and Aging (MSHA), which sampled all regions of the province of Manitoba. Baseline measures included age, gender, years of education, the Modified Mini-Mental State Examination (3MS), and rural/urban status. Rural was defined as a census subdivision with a population <20,000 and urban as 20,000...

Journal: :Journal of Alzheimer's disease : JAD 2012
Gregory J Tranah Michael A Nalls Shana M Katzman Jennifer S Yokoyama Ernest T Lam Yiqiang Zhao Sean Mooney Fridtjof Thomas Anne B Newman Yongmei Liu Steven R Cummings Tamara B Harris Kristine Yaffe

Mitochondrial dysfunction is a prominent hallmark of Alzheimer's disease (AD). Mitochondrial DNA (mtDNA) damage may be a major cause of abnormal reactive oxidative species production in AD or increased neuronal susceptibility to oxidative injury during aging. The purpose of this study was to assess the influence of mtDNA sequence variation on clinically significant cognitive impairment and deme...

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