نتایج جستجو برای: 4 michael addition
تعداد نتایج: 1922593 فیلتر نتایج به سال:
an efficient and environmentally friendly procedure for one-pot synthesis of 13-acetyl-9-methyl-11-ox-8-oxa-10,12-diazatricyclo [7.3.1. ] trideca-2,4,6-triene from salicylaldehyde, acetylaceton and urea via biginelli condensation and intramolecular michael-addition by using magnesium bromide as an expensive and easily available catalyst under solvent-free condition is desired. the structural el...
The anticoagulant racemic warfarin is synthesized by the Michael addition of 4-hydroxycoumarin with benzalacetone in the present of equimolar amounts of imidazolium based ionic liquids [bmim] BF4 and [bmim] Br and other reaction solvents such as H2O, pyridine and ammonia in five different tests. Also synthesis of a derivative of warfarin (2-methyl-4-phenyl pyrano [3, 2-c] chromen-5(4H)-one) und...
s | 41 diagnosis of PTSD. Finally, I will discuss aspects of the various trials that point to how NAC may be most effectively employed clinically in combination with psychosocial interventions, and perhaps other pharmacological treatments. Speaker 2: Olivia Dean, Australia Title: Minocycline as an adjunctive therapy for unipolar depression Dean OM1,2,3, Maes M4, Berk L1, Ashton M1, Kanchanatawa...
A useful Michael addition reaction using nitroalkanes as the nucleophile and 4-oxo-enoates as the Michael acceptor has been disclosed, and the reaction allows expedient access to functionalized chiral gamma-keto esters in high yields and excellent enantioselectivities (up to 98% ee), with a low catalyst loading.
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