Extreme instability of pyrimidine motif triplex DNA at physiological pH severely limits its use in an artificial control of gene expression in vivo. Stabilization of the pyrimidine motif triplex at physiological pH is, therefore, crucial in improving its therapeutic potential. To this end, we have investigated the thermodynamic and kinetic effects of our previously reported chemical modificatio...

OBJECTIVES/HYPOTHESIS Electromechanical reshaping (EMR) involves reshaping cartilage by mechanical deformation and delivering electric current to the area around the bend axis, causing local stress relaxation and permanent shape change. The mechanism of EMR is currently unclear, although preliminary studies suggest that voltage and application time are directly related to the concentration and ...

The objectives of this study were to evaluate the influence of diet composition on ruminal parameters, more particularly redox potential (Eh). Four Holstein dry dairy cows, fitted with ruminal cannulas, were allocated in a 4 × 4 Latin square design. They were given four experimental hay-based diets D0, D25, D42 and D56 consisting of 0%, 25%, 42% and 56% of ground wheat and barley concentrate mi...

Visible and near infrared reflectance spectroscopy was used to predict pH at 24h (pH24) post-mortem, sarcomere length (SL), cooking loss (CL), Warner-Bratzler Shear Force (WBSF) and colour parameters (L(∗), a(∗), b(∗)) in beef cattle samples. Samples from M. longissimus thoracis et lumborum from 30 bulls were aged at 4°C for 1, 3, 7 and 14 days and analysed for pH, SL, CL, WBSF and colour. NIRS...

Five different activated carbons (ACs) have been prepared from dried date pits using air and phosphoric acid as activating agents. The used phosphoric acid:date pit ratio dictated the characteristics of the prepared ACs; the equivalent BET-nitrogen surface area varied from 794 m²/g for a ratio of 5:1, to 1707 m²/g for a ratio of 2:1, whereas the micropore volume changed in value from 0.24 cm³/g...

abstract understanding distribution of physical and chemical soil parameters is very important in recognizing, planning, and soil and water resources management in precision agriculture. regard to the problems related to direct measurement, finding solution to estimate these parameters are very essential. the purpose of this study was to evaluate the spatial variation of some soil parameters su...

In order to see the influence of different variable parameters (initial pH of the solution, Fe++ concentration and H2O2 concentration) and the efficiency to remove Malachite Green dye (Basic Green 4) from aqueous solution, Fenton Oxidation method was employed. Then different parameters were studied using known concentration (150 mg/l) and initial COD (256 mg/l) of prepared dye synthetic solutio...

AIMS Acute Helicobacter pylori infection is associated with transient hypochlorhydria. In H pylori-associated atrophy, hypochlorhydria has a role in iron deficiency (ID) through changes in the physiology of iron-complex absorption. The aims were to evaluate the association between H pylori-associated hypochlorhydria and ID in children. METHODS Symptomatic children (n=123) were prospectively e...