Abstract Background Cervical cancer is one most common types among females over the world. While its underlying mechanisms remain unclear. Circ-CCDC66 has been revealed to participate in multiple biological functions, and contribute various diseases’ progression. In current study, we aimed demonstrate role of circ-CCDC66 cervical Methods Real-time quantitative PCR (RT-qPCR) was conducted measur...

Abstract Background Meckel’s diverticulum is the most prevalent congenital anomaly of gastrointestinal tract with an estimated prevalence ranging from 2% to 4%. The a remnant vitelline duct, which leads formation true containing all layers small intestine. condition usually clinically silent; however, it can present unusual symptoms and signs therefore result in delayed diagnosis, particularly ...

Numerous studies have demonstrated that a class of long noncoding RNAs (lncRNAs) are dysregulated in hepatocellular carcinoma (HCC) and they are closely related with tumorigenesis. Our previous studies indicated that LINC00052 was a downregulated lncRNA in HCC and acted as a tumor suppressor gene. Using transcription microarray analysis, we found that knockdown of LINC00052 resulted in EPB41L3 ...

Malignant melanoma is highly lethal due to its aggressive invasive properties and metastatic dissemination. The transcription factor E2F1 is crucial for melanoma progression through poorly understood mechanisms. Here, we show that the miR-224/miR-452 cluster is significantly increased in advanced melanoma and invasive/ metastatic cell lines that express high levels of E2F1. miR-224/miR452 expre...

Constitutive E-selectin expression on dermal microvascular endothelial cells plays a critical role in mediating rolling adhesive interactions of human skin-homing T cells and in pathologic accumulation of lymphocytes in skin. The major E-selectin ligand on human skin-homing T cells is cutaneous lymphocyte-associated antigen (CLA), a specialized glycoform of P-selectin glycoprotein ligand-1 (PSG...

Background: Tuberculosis progresses despite potent Thl responses. A putative explanation is the presence of a subversive Th2 response. However interpretation is confounded by a novel cytokine, IL-452, a splice variant and inhibitor of IL-4. Methods: The expression of Thl cytokines (IFN-y), IL-452, Th2 cytokines (IL-4) and sCD30 was investigated in whole blood, lung lavage and mononuclear cell c...

TAB1 was defined as a regulatory subunit of the protein kinase TAK1, which functions upstream in the pathways activated by interleukin (IL)-1, tumor necrosis factor (TNF), toll-like receptors (TLRs) and stressors. However, TAB1 also functions in the p38 MAPK pathway downstream of TAK1. We identified amino acids (aa) 452/453 and 456/457 of TAB1 as novel sites phosphorylated by TAK1 as well as by...

ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Graczyk A, Waśkiel-Burnat Rakowska Rudnicka L. The use of minoxidil in diseases associated with hair loss. Dermatology Review/Przegląd Dermatologiczny. 2022;109(6):437-452. doi:10.5114/dr.2022.126603. APA Graczyk, A., Waśkiel-Burnat, Rakowska, & Rudnicka, (2022). Dermatologiczny, 109(6), 437-452. https://doi.org/1...