Departamento de Engenharia Mecânica, Instituto Superior de Engenharia do Porto, Instituto Politécnico do Porto, Rua Dr. António Bernardino de Almeida, 431, 4200-072 Porto, Portugal b Faculdade de Economia e Gestão, Universidade Lusófona do Porto, Rua Augusto Rosa, 24, 4000-098 Porto, Portugal c Faculdade de Engenharia da Universidade do Porto, Rua Dr. Roberto Frias, s/n, 4200-465 Porto, Portuga...

This essay looks at the historical significance or two APS papers that are freely available online: Goldberg JM and Brown PB. Response of binaural neurons of dog superior olivary complex to dichotic tonal stimuli: some physiological mechanisms of sound localization, J Neurophysiol 32: 613–636, 1969 (http://jn.physiology.org/cgi/ reprint/32/4/613). Yin TCT and Chan J. Interaural time sensitivity...

Epoxide hydrolases (EH) catalyze the hydrolysis of epoxides and arene oxides to their corresponding diols. The crystal structure of murine soluble EH suggests that Tyr(465) and Tyr(381) act as acid catalysts, activating the epoxide ring and facilitating the formation of a covalent intermediate between the epoxide and the enzyme. To explore the role of these two residues, mutant enzymes were pro...

The development of new effective drug to stimulate the spermatogenesis on the patients with various causes of male infertility has been proposed in the clinical field. We studied the usefulness of the two herbal extract mixtures, KH-465, consisted of Epimedium Koreanum and Angelica Gigas as a spermatogenesis enhancer. Experimental spermatogenic failure was made by administrating leuprolide acet...

The development of new effective drug to stimulate the spermatogenesis on the patients with various causes of male infertility has been proposed in the clinical field. We studied the usefulness of the two herbal extract mixtures, KH-465, consisted of Epimedium Koreanum and Angelica Gigas as a spermatogenesis enhancer. Experimental spermatogenic failure was made by administrating leuprolide acet...

We report the discovery of a 206 ms pulsar associated with the TeV γ-ray source HESS J1640−465 using the Nuclear Spectroscopic Telescope Array (NuSTAR) X-ray observatory. PSR J1640−4631 lies within the shell-type supernova remnant (SNR) G338.3−0.0, and coincides with an X-ray point source and putative pulsar wind nebula (PWN) previously identified in XMM-Newton and Chandra images. It is spinnin...

Objective: The development of new effective drug to stimulate the spermatogenesis on the patients with various causes of male infertility has been proposed in the clinical field. We studied the usefulness of the two herbal extract mixture, KH-465, consisted of Epimedium Koreanum and Angelica Gigas as a spermatogenesis enhancer. Methods: Experimental spermatogenic failure was made by administrat...

We present X-ray observations of the as of yet unidentified very high-energy (VHE) γ-ray source HESSJ1640–465 with the aim of establishing a counterpart of this source in the keV energy range, and identifying the mechanism responsible for the VHE emission. The 21.8 ksec XMM-Newton observation of HESSJ1640– 465 in September 2005 represents a significant improvement in sensitivity and angular res...