In an attempt to better understand the molecular mechanism of action of the antipsychotic lead LASSBio-579 and of its main metabolite LQFM 037, the aim of this work was to evaluate their intrinsic activity and binding kinetics at the dopamine D2 receptor. In transfected HEK cells expressing the D2L receptor under an inducible promoter, LASSBio-579 and LQFM 037, but not clozapine, behaved as wea...

Abstract. Objective: The authors assessed associations between body weight perception and weight loss strategies. Participants: They randomly selected male and female college students (N = 38,204). Methods: The authors conducted a secondary data analysis of the rates of weight loss strategies and body weight perception among students who completed the National College Health Assessment survey. ...

N. HUTCHINS and IVAN MARUSIC Journal of Fluid Mechanics / Volume 579 / May 2007, pp 1 ­ 28 DOI: 10.1017/S0022112006003946, Published online: 02 May 2007 Link to this article: http://journals.cambridge.org/abstract_S0022112006003946 How to cite this article: N. HUTCHINS and IVAN MARUSIC (2007). Evidence of very long meandering features in the logarithmic region of turbulent boundary layers. Jour...

*Correspondence: [email protected] 1College of Mathematics and Systems Science, Shandong University of Science and Technology, Qianwangang Road 579, Qingdao, 266590, P.R. China 2State Key Laboratory of Mining Disaster Prevention and Control Co-founded by Shandong Province and the Ministry of Science and Technology, Shandong University of Science and Technology, Qianwangang Road 579, Qi...

Erythrosine (FD&C Red No. 3) is widely used as a coloring agent for foods, beverages, pharmaceutical preparations, and cosmetics. It has been evaluated for acceptable daily intake by the Joint FAO/WHO Expert Committee on Food Additives (see Annex 1, Ref. Nos. 8, 19 & 35) in 1964, 1969 and 1974. At the 18th Meeting (1974) of the Committee, an ADI of 0 2.5 mg/kg body weight was allocated. Toxicol...

OBJECTIVE A study was made of heart transplant patient perception of the influence of oral health upon quality of life, based on the Oral Health Impact Profile (OHIP-49) questionnaire validated for Spanish speaking subjects. DESIGN A cross-sectional evaluation was made of the heart transplant patients followed-up on in the Heart Transplantation Unit of Reina Sofía University Hospital (Spain),...

Cordoba, 6 May 2016. Promoting early diagnosis, treating the disease in specialized centers from a multidisciplinary perspective and fostering access to new therapies are three of the essential steps to be taken to improve the prognosis of ovarian cancer. This is one of the main conclusions set out today at the 5 Ovarian Cancer Forum hosted by PharmaMar at the Hospital Universitario Reina Sofía...

This is the final version of the manuscript. It is the peer reviewed version of the following article: Christ, A., Herzog, K. and Willnow, T. E. (2016), LRP2, an auxiliary receptor that controls sonic hedgehog signaling in development and disease. Dev. Dyn., 245: 569–579. doi:10.1002/dvdy.24394 which has been published in final form in: Developmental Dynamics 2016 MAY; 245(5): 569-579 2016 MAR ...

Junling Zhang 1,2,*, Gajanan G. Hegde 2, Jennifer Shang 2 and Xiaowen Qi 2,3 1 College of Economics and Management, Zhejiang Normal University, Jinhua 321004, China 2 Katz Graduate School of Business, University of Pittsburgh, Pittsburgh, PA 15260, USA; [email protected] (G.G.H.); [email protected] (J.S.); [email protected] (X.Q.) 3 College of Business Administration, Zhejiang Universit...