This study was conducted to examine and compare the clinical response of patients with small hemangiomas treated with two non-ablative lasers with wavelength radiation 755 nm and 595 nm. The treatment efficacy – curative effect and loss of pigment and appearance of scars were compared using Pearson’s chi-square test. The therapeutic effect of 595 nm laser radiation was very high – almost 100%. ...

Binding of GH to GH receptor (GHR) rapidly and transiently activates multiple signal transduction pathways that contribute to the growth-promoting and metabolic effects of GH. While the events that initiate GH signal transduction, such as activation of the Janus tyrosine kinase JAK2, are beginning to be understood, the signaling events that terminate GH signaling, such as dephosphorylation of t...

As a kind of congenital vascular malformations, Port Wine Stain (PWS) is composed of ectatic venular capillary blood vessels buried within healthy dermis. In clinic, Pulsed Dye Laser (PDL) in visible band (e.g. 585 or 595 nm) together with cryogen spray cooling has become the golden standard for treatment of PWS. However, due to the limited energy penetration depth of the PDL, deeply buried blo...

We investigated the functional consequences following deletion of a microRNA (miR) termed miR-595 which resides on chromosome 7q and is localised within one of the commonly deleted regions identified for Myelodysplasia (MDS) with monosomy 7 (-7)/isolated loss of 7q (7q-). We identified several targets for miR-595, including a large ribosomal subunit protein RPL27A. RPL27A downregulation induced...

BACKGROUND Despite the proven effectiveness of the 595-nm pulsed dye laser (PDL) in treating superficial infantile hemangiomas, many physicians are reluctant to treat such lesions involving the eyelid. OBJECTIVE To examine the safety and efficacy of the 595-nm PDL for the treatment of superficial infantile hemangiomas of the eyelid. MATERIALS & METHODS Records were reviewed for patients with ...

Will the initiator of fatty acid synthesis in Pseudomonas aeruginosa 1 please stand up? 2 3 4 Yong-Mei Zhang and Charles O. Rock* 5 Department of Biochemistry and Molecular Biology, Medical University of South Carolina, 6 Charleston, SC 29425 and Department of Infectious Diseases, St. Jude Children’s Research 7 Hospital, Memphis, TN 38105 8 9 10 *Mailing address: Department of Infectious Diseas...

The Rockefeller University Press $30.00 J. Cell Biol. Vol. 209 No. 4 595–608 www.jcb.org/cgi/doi/10.1083/jcb.201409142 JCB 595 *L. Luo, H. Wang, and C. Fan contributed equally to this paper. Correspondence to Yu Cai: [email protected] Abbreviations used in this paper: Arm, Armadillo; Bam, bag of marbles; CB, cystoblast; ChIP, chromatin immunoprecipitation; Dally, division abnormally delayed; Dpp...