El presente texto realiza una reseña del libro de Esteban Fernández-Cobián: "Arquitectura religiosa siglo XXI en España" (2019). ISBN: 978-84-9749-759-6.

ous chemical or electrochemical systems mimicking monooxygenase enzymes have been reported. Among these oxygenation models, studies on chemical systems using iron(III) picolinate (Fe(PA)3) or iron(II) picolinate (Fe (PA)2) complexes as catalysts have been reported under various conditions and in various solvents. We are interested in stereoselective oxidation reactions, especially 7a-hydroxylat...

The placenta forms a selective barrier that functions to transport nutrients and fetal wastes in the appropriate directions. Syncytiotrophoblasts, which form the surface of the placental villi, play an essential role in restricting drug import through the blood-placenta barrier (BPB) to the fetus (Chart 1). The apical surface of the syncytiotrophoblast layer is the maternal-facing membrane, and...

OBJECTIVE To investigate the associations between psychosocial factors and peripheral blood CD4 and CD8 T lymphocyte numbers in Brazilian peacekeepers. METHODS Venous blood was collected from 759 peacekeepers who had just returned from a peace mission in Haiti. Among the 759 soldiers, 642 individuals completed the psychosocial measures. CD4 and CD8 T lymphocyte counts were measured by flow cy...

BACKGROUND CARP-1/CCAR1, a perinuclear phospho-protein, regulates signaling by adriamycin, steroids, or growth factors. However, intracellular events that regulate CARP-1-dependent cell growth are not fully understood. RESULTS Here we investigated whether CARP-1 is involved in signaling induced by the protein kinase A inhibitor H89. Treatments of human breast cancer cells with H89 resulted in...

Stimulation of the IL-6R complex leads to Src homology domain containing tyrosine phosphatase 2 (SHP2) recruitment to the receptor subunit gp130 and its subsequent tyrosine phosphorylation. SHP2 is a two-SH2 domain-containing protein tyrosine phosphatase that is activated by many cytokines and growth factors. SHP2 counteracts the activation of transcription factors of the STAT family and the in...

Extracellular signal-regulated kinases (ERKs) phosphorylate the high molecular mass isoform of the actin-binding protein caldesmon (h-CaD) at two sites (Ser(759) and Ser(789)) during smooth muscle stimulation. To investigate the role of phosphorylation at these sites, antibodies were generated against phosphopeptides analogous to the sequences around Ser(759) and Ser(789). Affinity-purified ant...