Igor Tchivilev, Nageswara R. Madamanchi, Aleksandr E. Vendrov, Xi-Lin Niu, and Marschall S. Runge Department of Medicine, Carolina Cardiovascular Biology Center, University of North Carolina, Chapel Hill, North Carolina 27599-7126 Running Title: PP1cγ1 regulates apoptosis in vascular smooth muscle cells 1 Both authors contributed equally to this work. *Address for Correspondence:Marschall S. Ru...

the aim of this research was to compare more and less competitiveness of rice cultivars against barnyardgrass for light extinction coefficient and canopy structur. a filed experiment was conducted in 2007 growing season in tonekabon’s rice research station in mazandaran province. the experiment layout was a factorial design with four randomized complete blocks. seven rice cultivars (khazar, sep...

Copyright: © 2015 Hilton EJ, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. *Corresponding author: Latha Hebbar, Department of Anesthesia and Perioperative Medicine, Medical University of South Carolin...

Cladosporium sphaerospermum, a dematiaceous saprophytic fungus commonly found in diverse environments, has been reported to cause allergy and other occasional diseases in humans. However, its basic biology and genetic information are largely unexplored. A clinical isolate C. sphaerospermum genome, UM 843, was re-sequenced and combined with previously generated sequences to form a model 26.89 Mb...

The activity of a new, soluble and stable polyene (SPA-S-843) against Candida albicans was assessed by contact and culture tests and by inhibition of germ-tube formation. The drug demonstrated a higher contact activity and lower MICs than amphotericin B. This antimicrobial activity was more evident under acid pH and low ionic strength. In addition, the ability of SPA-S-843 to inhibit Candida sp...

The present work deals with the antifungal activity of SN 105-843 (Naftifine) against dermatophytes in vivo. Fifty cases suffering from various types of dermatomycoses were studied from November 1979 to September l980. The patients were supplied with 1% gel preparation of SN 105-843 for local application on the lesion for a period of 2-8 weeks. The results indicate that the drug has very signif...

Staphylococcus aureus protein A (SpA) is the most popular affinity ligand for immunoglobulin G1 (IgG1). However, the molecular basis for the dissociation dynamics of SpA-IgG1 complex is unclear. Herein, coarse-grained (CG) molecular dynamics (MD) simulations with the Martini force field were used to study the dissociation dynamics of the complex. The CG-MD simulations were first verified by the...