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Aberrant overexpression of the miR-17-92 polycistron is strongly associated with B-cell lymphomagenesis. Recent studies have shown that miR-17-92 down-regulates the proapoptotic protein Bim, leading to overexpression of Bcl2, which likely plays a key role in lymphomagenesis. However, the fact that Jeko-1 cells derived from mantle cell lymphoma exhibit both homozygous deletion of BIM and overexp...
This Article is brought to you for free and open access by the Physics at ODU Digital Commons. It has been accepted for inclusion in Physics Faculty Publications by an authorized administrator of ODU Digital Commons. For more information, please contact [email protected]. Repository Citation Bosted, P. E.; Dharmawardane, K. V.; Dodge, G. E.; Forest, T. A.; Kuhn, S. E.; Prok, Y.; Adams, G.;...
BACKGROUND Granulocyte colony-stimulating factor (G-CSF)-producing esophageal squamous cell carcinoma (ESCC) has been considered to have a poor prognosis. We successfully treated a case of G-CSF-producing ESCC in a 92-year-old woman. CASE PRESENTATION A 92-year-old woman was admitted to our hospital with the complaints of choking while swallowing and dysphagia. Esophagogastroduodenoscopy and ...
Let G be a graph of order n ≥ 3. An even squared hamiltonian cycle (ESHC) of G is a hamiltonian cycle C = v1v2 . . . vnv1 of G with chords vivi+3 for all 1 ≤ i ≤ n (where vn+j = vj for j ≥ 1). When n is even, an ESHC contains all bipartite 2-regular graphs of order n. We prove that there is a positive integer N such that for every graph G of even order n ≥ N , if the minimum degree δ(G) ≥ n 2 +...
Zum Beitrag: Bertsch T, Erbacher G. Lipödem – Mythen und Fakten Teil 1. Phlebologie 2018; 47: 84–92.
Biostimulation is one of the most mature methods of bioremediation of hydrocarbons, yet recent advances in geophysics, stable isotope analyses, and molecular microbiology promise dramatic increases in the depth, breadth, and throughput of biostimulation strategies. Using a systems biology approach we can now understand not only what microbes are present, but their in situ activities to trace nu...
Experiencing cultural heritage is a voyage of discovery and learning, where emerging insights and serendipity play a significant role. The experience also happens in a blended personal and social context. At the broader level, engagement is longitudinal – what we learn from modern cultural experiences (daily life in our surroundings) can provide clues to analogous interests in cultural material...
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