AIM The aim of this study was to assess the degree of alterations of renal function by using 99m-technetium dimercaptosuccinic acid ((99m)Tc-DMSA) and 99m-technetium diethylenetriaminepentaacetic acid ((99m)Tc-DTPA) scintigraphy in spinal cord injury (SCI) patients. MATERIAL AND METHODS Twenty-two consecutive SCI (15 paraplegic and 7 tetraplegic) patients (mean age: 49.1±13.4 years) who had n...

urinary tract infection (uti) is a common disease in childhood specially in female. in this study 50 patients with stablished diagnosis of uti were evaluated by both renal scan with tc-99m dmsa and renal sonography. the study revealed that most urinary tract infections are in children, female sex between 5-9 years of age. therefore the most important complications (renal scarring) are also comm...

twenty-one patients with medullary thyroid carcinoma were studied prospectively with tc-99m (v) dmsa after surgery. pentavalent dmsa scintigram demonstrated abnormal uptake in 13 and equivocal uptake in 6 patients. finally, seven patients with surgical or other imaging documentation were selected for this paper. most of these patients were asymptomatic. six patients had hypercalcitonemia and se...

Noninvasive analysis of renal function in conscious mice is necessary to optimize the use of mouse models. In this study, we evaluated whether single photon emission-computed tomography (SPECT) using specific radionuclear tracers can be used to analyze changes in renal proximal tubule functions. The tracers included (99m)TC- dimercaptosuccinic acid ((99m)Tc-DMSA), which is used for cortex imagi...

© 2008 Elsevier. All rights reserved. The pentavalent Tc-99m dimercaptosuccinic acid (Tc99m (V) DMSA, Tc(V)-DMSA) radiotracer has become more widely used. The accumulation of Tc(V)-DMSA in tumors was first reported in 1981 [1], and this tracer has subsequently been shown to localize in a variety of tumors [2,3]. Tc(V)-DMSA has also been used to depict abscesses and other inflammatory lesions [4...

Twenty-one patients with medullary thyroid carcinoma were studied prospectively with Tc-99m (V) DMSA after surgery. Pentavalent DMSA scintigram demonstrated abnormal uptake in 13 and equivocal uptake in 6 patients. Finally, seven patients with surgical or other imaging documentation were selected for this paper. Most of these patients were asymptomatic. Six patients had hypercalcitonemia ...

We present a case of phyllodes tumor of the breast in a 78-year-old woman evaluated with Tc-99m (V)DMSA and Tc-99m MIBI scintimammography, acquired in separate sessions (10 and 60 min post-injection). Tc-99m (V)DMSA was accumulated intensely within the mass [tumor to background ratio (T/B) >3], whereas Tc-99m MIBI had significantly lower uptake (T/B 1.9). Histology revealed a phyllodes tumor (m...

PURPOSE To examine whether (99m)Tc(V)-DMSA could be used as a non-invasive measure of cancer cell proliferation. METHODS Human breast cancer MCF-7, MDA-MB-231 and pII, and prostate cancer PC-3 cell lines were grown to 30, 50 and 100% confluency and pulsed with (99m)Tc(V)-DMSA in media for 60 min at 37°C. DNA synthesis was analysed by quantification of the S phase using flow cytometry, [methyl...

UNLABELLED (99m)Tc-Dimercaptosuccinic acid (DMSA) scintigraphy is a frequently used diagnostic test to assess the presence and severity of cortical damage. The aim of this study is to investigate the variability in the interpretation of (99m)Tc-DMSA scans, evaluate the usefulness of oblique images, and assess their impact on scan interpretation. METHODS Two experienced nuclear medicine physic...

Radiopharmaceuticals are known to interact with the blood components (i.e. the red blood cells, serum proteins etc) but so far, there have been no data regarding their purely mechanical trapping in thrombi. The experiments presented in this communication provide evidence that the technetium-99m labeled albumin macroaggregate ((99m)Tc-MAA), apparently due to its particle size, can be almost quan...