OBJECTIVE Left ventricular mass is an important determinant of diagnosis and prognosis in patients with heart disease. The aim of the present study was to validate measurement of the left ventricular mass index (LVMI) by quantitative gated myocardial SPECT (QGS) with 99mTc-tetrofosmin by comparing it with echocardiography. METHODS QGS and M-mode echocardiography (Echo) were performed within o...

Soft-tissue attenuation artifacts generally appear as fixed perfusion-scan defects. Gated 99mTc-tetrofosmin SPECT may help differentiate myocardial infarction (MI) from artifacts, as fixed defects with decreased function (wall motion and thickening) probably represent MI, whereas attenuation artifacts represent preserved function. Methods: Ungated stress and gated rest 99mTc-tetrofosmin SPECT w...

OBJECTIVE The purpose of this study was to clarify the usefulness of 99mTc-sestamibi (MIBI) delayed imaging in the assessment of the severity of myocardial ischemia in patients with coronary artery stenosis. METHODS Forty-three angina pectoris with coronary stenosis of greater than 75% were enrolled in this study. Myocardial perfusion SPECT images were obtained 1 and 6 hours after an intraven...

UNLABELLED The present study assessed left ventricular performance during dobutamine stress measured using gated SPECT, and compared the results to myocardial perfusion and fatty acid metabolism. METHODS Thirty-six patients with myocardial infarction given (99m)Tc-sestamibi or (99m)Tc-tetrofosmin were examined by gated SPECT at rest and during dobutamine stress (4-20 microg x kg(-1) x min(-1)...

We present the case of a 65-year-old man with dyspnea and chest discomfort referred for dipyridamole myocardial perfusion scintigraphy. 99mTc-sestamibi cardiac gated SPECT images showed an irreversible hypoperfusion in the mid-ventricular portion of anteroseptal wall, a suspicious reversible hypoperfusion in the apical slices of inferolateral wall, and left ventricle dilatation with a ejection ...

BACKGROUND Exercise gated single-photon emission computed tomography (SPECT) using technetium-99m (99mTc)-sestamibi evaluates both myocardial perfusion during stress and wall motion >30 min after the stress, which has the potential to assess not only exercise-induced myocardial ischemia but also the development of myocardial stunning. METHODS AND RESULTS To evaluate the incidence of post-stre...

Previously, technetium-99m-stannous pyrophosphate (99mTc-PPi) has been used to localize and estimate the size of myocardial infarcts in animals after permanent coronary artery occlusion. This study tested the hypothesis that 99mTc-PPi accurately sizes myocardial infarctions produced by temporary coronary artery occlusion and reflow in dogs. Three groups of dogs were studied: group A underwent 3...

Background: proper assessment of patients with ischemic cardiomyopathy is a key determinant for management other investigations, improving the patient’s quality life and reducing future cardiac events. This study was conducted to evaluate value myocardial MIBI washout rate using delayed resting perfusion imaging in limited resources countries. Patients Methods: this prospective included 86 (64 ...

UNLABELLED We assessed Takotsubo (ampulla) cardiomyopathy compared with acute coronary syndrome (ACS) using two-dimensional echocardiography and 99mTc-tetrofosmin myocardial SPECT. METHODS We examined 10 patients with Takotsubo cardiomyopathy and 16 with ACS at the time of emergency admission (acute phase), at three to nine days after the attack (subacute phase) and at one month after the att...

99mTc-sestamibi has been investigated as a potential viability marker; initial studies have shown good concordance between 201Tl and 99mTc-sestamibi activities in both viable and nonviable myocardium. However, assessment of myocardial viability by 99mTc-sestamibi remains controversial for tissue recovery after revascularization. Here, we present a patient with several regions of severely dimini...