In the near future, design of a new generation of drugs targeting proteins will be required. Considering the complex bond between the drug and protein, the structure and stability of the target protein should be considered. So far, a series of in vitro investigations have been conducted with the aim of predicting drug-biological medium interactions. In these studies, use of spectroscopic method...

DNA/RNA, present in almost every cell, has been a hot research topic in a wide range of areas, including biology, physics, chemistry and polymer engineering. Naturally, to image DNA and facilitate DNA/RNA-related questions becomes an interesting question itself. Since 50 years ago people have been discovering and developing families of fluorescence dyes (from Acridine orange to YOYO-1) with uni...

The electric and optical properties of molecules are commonly investigated by measurements of their absorption and fluorescence spectra, both in pure solvents of different polarities [1] and in mixed solvents [2]. The molecules benzophenone (BF), 2-aminobenzophenone (2ABF) and 4-aminobenzophenone (4ABF) investigated in this paper show no fluorescence at room temperature. Their absorption spectr...

in the near future, design of a new generation of drugs targeting proteins will be required. considering the complex bond between the drug and protein, the structure and stability of the target protein should be considered. so far, a series of in vitro investigations have been conducted with the aim of predicting drug-biological medium interactions. in these studies, use of spectroscopic method...

The synthesis, comprehensive linear photophysical characterization, two-photon absorption (2PA), steady-state and time-resolved stimulated emission depletion properties of a new fluorene derivative, (E)-1-(2-(di-p-tolylamino)-9,9-diethyl-9H-fluoren-7-yl)-3-(thiophen-2-yl)prop-2-en-1-one (1), are reported. The primary linear spectral properties, including excitation anisotropy, fluorescence life...

OBJECTIVE At 380 nm excitation, cervical tissue fluorescence spectra demonstrate characteristic changes with both patient age and the presence of dysplasia. A Monte Carlo model was developed in order to quantitatively examine how intrinsic NADH and collagen fluorescence, in combination with tissue scattering and absorption properties, yield measured tissue spectra. METHODS Excitation-emission...

Absorption spectra and fluorescence properties o f 2,3-dihydro-4( 1 H)-quinolinone deriva­ tives were studied at room temperature in different solvents. It has been found that the fluo­ rescence quantum yields and fluorescence decay times strongly depend on the molecular struc­ ture and solvent polarity. The character and the energy o f excited states were determined by PPP and CNDO /S quantum-...

a graphene oxide-terpyridine conjugate (gotc) based colorimetric and fluorescent nano-chemosensor was synthesized. it showed high selectivity and sensitivity for fe2+ and fe3+ ions in neutral aqueous solution over other metal ions such as li+, na+, ba2+, ca2+, al3+, cd2+, co2+, cu2+, hg2+, mn2+, ni2+, pb2+, zn2+, cr3+ and ag+. in absorption spectra, upon addition of fe2+ or fe3+, the sensor dis...

A series of asymmetrically substituted free-base di- and tetra-phenylporphyrins and the associated Zn-phenylporphyrins were synthesized and studied by X-ray diffraction, NMR, infrared, electronic absorption spectra, as well as fluorescence emission spectroscopy, along with theoretical simulations of the electronic and vibration structures. The synthesis selectively afforded trans-A₂B₂ porphyrin...