نتایج جستجو برای: acanthocytes
تعداد نتایج: 102 فیلتر نتایج به سال:
An adult male with severe tic disorder presented with recurrent injury to tongue and dysphagia. There were a significant excess of acanthocytes in the peripheral blood smear. Treatment with lithium resulted in a considerable reduction in the severity of tics and self-injurious behaviour.
chronic anemia is common in liver cirrhosis. in this setting the pathogenesis of anemia is complex and multifactorial. spur cell anemia is a serious disorder in cirrhotic patients associated with poor prognosis. liver transplantation constitutes the only therapeutic tool. we report a case of a severe spur cell anemia in alcoholic liver cirrhosis. in the attempt to investigate the origin of the...
UNLABELLED Chorea-acanthocytosis is an uncommon neurodegenerative disorder, usually with a low rate of progression. It is characterized by Huntington disease-like involuntary movements, cognitive decline, behavioral changes, seizures and polyneuropathy. Chorea-acanthocytosis belongs to the group of neuroacanthocytosis syndromes, a group of genetically defined diseases associated with progressiv...
Erythrocyte membrane changes of chorea-acanthocytosis are the result of altered Lyn kinase activity.
Acanthocytic RBCs are a peculiar diagnostic feature of chorea-acanthocytosis (ChAc), a rare autosomal recessive neurodegenerative disorder. Although recent years have witnessed some progress in the molecular characterization of ChAc, the mechanism(s) responsible for generation of acanthocytes in ChAc is largely unknown. As the membrane protein composition of ChAc RBCs is similar to that of norm...
OBJECTIVE The presence of hematuria has been suggested to indicate nondiabetic nephropathy in diabetic patients with proteinuria. However, hematuria is frequently found in patients with biopsy-proven diabetic glomerulosclerosis without nondiabetic nephropathy. Urine microscopy allows discrimination of glomerular hematuria, which is defined as acanthocyturia (urinary excretion of acanthocytes, w...
Experiments reported in the accompanying paper (1) showed that an abnormally high percentage of red cells from patients with acanthocytosis hemolyze when incubated at 370 or 40 C for 48 hours. This abnormal lysis was inhibited by heparin, supplementary glucose, and additions of normal serum. This report partially identifies the components of normal serum that inhibit such autohemolysis and the ...
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