Acetylation with acetic anhydride is well known to improve the dimensional stability and durability of wood. Veneer appealing for acetylation because its thin thickness, which supports a complete even impregnation difficult-to-treat wood species, such as beech (Fagus sylvatica L.). Unlike resin-based veneer impregnation, acetylated does not require any additional curing. As result, properties a...

Acetylation is frequently detected on mitochondrial enzymes, and the sirtuin deacetylase SIRT3 is thought to regulate metabolism by deacetylating mitochondrial proteins. However, the stoichiometry of acetylation has not been studied and is important for understanding whether SIRT3 regulates or suppresses acetylation. Using quantitative mass spectrometry, we measured acetylation stoichiometry in...

Nε-Lysine acetylation has been recognized as a ubiquitous regulatory posttranslational modification that influences a variety of important biological processes in eukaryotic cells. Recently, it has been realized that acetylation is also prevalent in bacteria. Bacteria contain hundreds of acetylated proteins, with functions affecting diverse cellular pathways. Still, little is known about the re...

wood is a porous three dimensional, hydroscopic, viscoelastic, anisotropic bio-polymer composite composed of an interconnecting matrix of cellulose, hemicelluloses and lignin with minor amounts of inorganic elements and organic extractives. some, but not all, of the cell wall polymer hydroxyl groups are accessible to moisture and these accessible hydroxyls form hydrogen bonds with water. as the...

Abstract Lysine-ε-acetylation (Kac) is a post-translational modification (PTM) that critical for metabolic regulation and cell signaling in mammals. However, its prevalence importance plants remain to be determined. Employing high-resolution tandem mass spectrometry, we analyzed protein lysine acetylation five representative Arabidopsis organs with 2 ~ 3 biological replicates per organ. A total...

influences of the wood fiber acetylation as well as the compatibilizer mapp on water absorption, thickness swelling and dimensional stability of acetylated wood/ polypropylene composites (wpcs) were the main concerns of this research. wood fibers were acetylated with acetic anhydride without using any catalyst to achieve weight percent gains (wpgs) of 4.5, 7.5 and 17.6%. the acetylated fibers w...

histone acetylation, one of the first and best studied histone post-translational modifications (ptms), as well as the factors involved in its deposition (writers), binding (readers) and removal (erasers), have been shown to act at the heart of regulatory circuits controlling essential cellular functions. the identification of a variety of competing histone lysine-modifying acyl groups includin...

Regulation of histone acetylation is fundamental to the utilization of eukaryotic genomes in chromatin. Aberrant acetylation contributes to disease and can be clinically combated by inhibiting the responsible enzymes. Our knowledge of the histone acetylation system is patchy because we so far lacked the methodology to describe acetylation patterns and their genesis by integrated enzyme activiti...

Reversible acetylation of α-tubulin is an evolutionarily conserved modification in microtubule networks. Despite its prevalence, the physiological function and regulation of microtubule acetylation remain poorly understood. Here we report that macrophages challenged by bacterial lipopolysaccharides (LPS) undergo extensive microtubule acetylation. Suppression of LPS-induced microtubule acetylati...